Fosmanogepix, a prodrug of Manogepix (MGX), is a groundbreaking antifungal agent with broad-spectrum activity against yeasts, including and , as well as molds. It exhibits effectiveness against drug-resistant strains, such as strains resistant to and strains resistant to azoles. Furthermore, fosmanogepix shows activity against pathogens that typically resist other classes of drugs, such as , , and , although its efficacy against Mucorales varies.
View Article and Find Full Text PDFAcute chest syndrome (ACS) is a major cause of morbidity and mortality in patients with SCD (SCD). The analysis of research productivity and trends in ACS may serve as a valuable guide for investigators, institutions, and funding agencies to plan the future directions of research. The current review aims to evaluate the productivity and trends of publications related to ACS in adults by analyzing the top 100 most cited articles.
View Article and Find Full Text PDFBackground Antimicrobial resistance (AMR) has been designated a public health crisis by the World Health Organization. AMR can lead to escalated healthcare costs, higher mortality rates, increased morbidity, and more frequent hospitalizations. This study aimed to retrospectively evaluate the appropriateness of Tazocin prescription for community-acquired pneumonia (CAP).
View Article and Find Full Text PDFIntroduction Hepatitis C is a viral disease caused by the hepatitis C virus (HCV), a member of the family. This compact, enveloped RNA virus possesses a positive single-stranded genome and can be transmitted through various means, including blood exposure, sexual contact, and vertical transmission. The disease is associated with significant morbidity and mortality, imposing substantial costs on the healthcare system.
View Article and Find Full Text PDFBackground And Aim: Papillary thyroid carcinoma accounts for 85% of thyroid follicular epithelial-derived cancers. The identification of pathogenetic mechanisms improved the understating of papillary thyroid carcinoma pathogenesis. The current study aims to examine the research productivity and trends in the genetics of papillary thyroid carcinoma from 1991 to 2020.
View Article and Find Full Text PDFThis paper aims to examine the worldwide research development and trends in forensic anthropology by using bibliometric analysis. Scopus database was used to identify published papers on forensic anthropology from 1948 to 2020. A total of 4,499 records were analyzed for yearly publication productivity, authorship and citation pattern, types of documents, most productive journals, organizations, authors, and countries, frequently cited papers, most used keywords, countries of collaboration, and three-field plot analysis in the domain of forensic anthropology.
View Article and Find Full Text PDFNumerous studies have highlighted significant correlations between major psychiatric disorders and criminal behavior. However, the plethora of literature on criminality among patients with major psychiatric disorders originated in the West. The objective of the present paper is to review criminal behavior among individuals with mental illness in Arab countries.
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