Potential Involvement of Human Leukocyte Antigen-DR/DQ Polymorphisms with Schizophrenia Among Patients with Schizophrenia in Yemen.

Objectives: To evaluate the hypothesis that human leukocyte antigens (HLAs) confer susceptibility to schizophrenic disorders, by assessing their contribution to the risk of schizophrenia in a Yemeni population.

Methods: The researchers approached patients who had been diagnosed with schizophrenia at Al-Amal Hospital for Psychiatric Diseases, Sana'a. Controls were drawn randomly from the general population.

Comparison of the prevalence of malocclusion and oral habits between children with cerebral palsy and healthy children.

Background: Cerebral palsy (CP) represents for children an important problem of health and affects roughly 2 per 1000 live births and is the most common pediatric developmental motor disability. Therefore, the purpose of this study was to determine the prevalence, type and severity of malocclusion and oral habits in children with Cerebral Palsy (CP) and to compare them with a control group of healthy children in Sana'a city.

Materials And Methods: A prospective, case-control study was made of two groups, a cerebral palsy and a control group.

Prevalence of occult hepatitis B virus infection among patients receiving haemodialysis in Sana'a city.

Background: Occult hepatitis B virus infection (OBI) is a challenging entity. Due to the increase in invasive procedures, blood transfusions, and difficulties in diagnosing OBI, patients are more likely to acquire OBI. This cross-sectional study was conducted to assess the prevalence of OBI by hepatitis B virus (HBV)-DNA detection, the prevalence of HBV infection by total hepatitis B core antibody (HBcAb) detection, and the potential risk factors for HBV infection in patients receiving haemodialysis regularly.

sp. 1S1 isolated from Southern coast of the Red Sea as a renewable natural resource of several bioactive compounds.

Red Sea represents one of the most remarkable marine ecosystems. However, it is also one of the world's least explored areas of marine biodiversity. The aims of this investigation were therefore, to isolate marine microorganisms from the seashore sediments and water in shallow region from west Yemen coast, to assess their antimicrobial potential, to identify the highly active isolate, and to purify and identify the bioactive compounds from it.

Class 1 Integrons in Clinical Multi Drug Resistance , Sana'a Hospitals, Yemen.

Background And Objectives: The occurrence of multi-drug resistance (MDR) Escherichia coli is one responsible for raised mortality and morbidity and was reported as major health problem. Class 1 integrons has crucial role in distributing antibiotic resistance genes among bacteria. Present work was aimed to determine the prevalence of class 1 integrons and its association with antibiotic resistance in MDR E.

Human Leukocyte Antigen Class I and II Variants in Yemeni Patients with Chronic Renal Failure.

Background: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases.

Objective: To determine the association between variants of class I (A and B) and class II (DRB1) HLA alleles and chronic renal failure (CRF), compared with healthy controls, in Yemen.

Methods: A case-control study in the Urology and Nephrology Center at Al-Thawra University Hospital in Sana'a, Yemen was carried out between January 2013 and December 2015 and included 187 CRF patients, and 194 healthy controls visiting the same center for kidney donation.

Urinary Tract Infection among Renal Transplant Recipients in Yemen.

Urinary tract infection (UTI) is the most common complication following kidney transplantation (KT), which could result in losing the graft. This study aims to identify the prevalence of bacterial UTI among KT recipients in Yemen and to determine the predisposing factors associated with post renal transplantation UTI. A cross sectional study included of 150 patients, who underwent KT was conducted between June 2010 and January 2011.

The Association between Human Leukocyte Antigens and Hypertensive End-Stage Renal Failure among Yemeni Patients.

Objectives: Many studies have attempted to locate a connection between various genetic factors and the pathogenesis of certain diseases. A number of these have found human leukocyte antigens (HLAs) to be the most significant genetic factors affecting the susceptibility of an individual to a certain disease. The present case-control study aimed to determine the connection between class I and class II HLAs and cases of hypertensive end-stage renal failure (HESRF), as contrasted with healthy controls, in Yemen.

Clinical and laboratory manifestations of yemeni patients with systemic lupus erythematosus.

Objectives: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterised by multi-systemic involvement. This is the first study undertaken to determine the relationships between serological marker positivity and age, gender, signs and symptoms, risk factors and the treatment of SLE in Yemen.

Methods: We investigated the cases of 149 patients with SLE admitted to Al-Thawra Hospital in Sana'a city between November 2009 and November 2010.

Normalized real-time PCR for diagnosis of H. pylori infection.

Objectives: There is increasing interest in the use of quantitative PCR (q-PCR) for diagnosis of H. pylori infection. However, the assay remains largely unstandardized, making comparison between studies unreliable.

Prevalence of rabies in various species in yemen and risk factors contributing to the spread of the disease.

Objectives: This study aimed to describe for the first time the prevalence of the passively-reported rabies virus among different domestic and wild animals submitted to the Central Veterinary Laboratory from various areas in Yemen, and to study prevalence proportion ratios (PPR) that contributed to the spread of rabies among animals, and its transmission to humans.

Methods: A brain sample was obtained from each of the 180 animals and tested for rabies virus by a direct fluorescent antibody test.

Results: Out of the total number of animals involved in attacks on humans, 63.

Types of Bacteria associated with Neonatal Sepsis in Al-Thawra University Hospital, Sana'a, Yemen, and their Antimicrobial Profile.

Objectives: This study was undertaken to investigate the organisms causing sepsis in the Neonatal Unit at Al-Thawra Hospital, Sana'a, Yemen, determine their resistance to antibiotics, and recommend policy for empirical treatment.

Methods: A total of 158 neonates having one or more signs of sepsis, and aged from 0 to 28 days, were enrolled in this study. A blood sample was taken from each subject, cultured, and then antibacterial susceptibility tests were performed for isolates.

Hepatitis B Vaccine Coverage and the Immune Response in Children under ten years old in Sana'a, Yemen.

Objectives: The study was undertaken, first, to determine the coverage rate of hepatitis B (HB) vaccine and second to evaluate the immune response to HB vaccine among children under 10 years old by measuring the level of circulating anti-HB surface antigen (anti-HBs) antibodies after immunisation with three doses.

Methods: First, 840 children were randomly selected from 4 randomly selected sites in Sana'a city to study the coverage rate of the vaccine; of these, 504 children vaccinated against HBV prior to the study, were tested (56% males and 44% females). Sera were tested for anti-HBs antibodies by ELISA quantitative technique.

The therapeutic efficacy of sulfadoxine/pyrimethamine against Plasmodium falciparum in Yemen.

Objective: The aim of this study was to determine the sensitivities of Plasmodium falciparum clinical isolates to sulfadoxine/pyrimethamine (SP) using in vivo and in vitro methods.

Subjects And Methods: In vivo and Mark III in-vitro test techniques according to World Health Organization protocols of antimalarial drug tests were used to determine the SP susceptibility of the P. falciparum isolates from 100 malaria patients of both sexes between the ages of 3.

Assessment of antimalarial activity against Plasmodium falciparum and phytochemical screening of some Yemeni medicinal plants.

Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. In the present study, six selected plants (Acalypha fruticosa, Azadirachta indica, Cissus rotundifolia, Echium rauwalfii, Dendrosicyos socotrana and Boswellia elongata) commonly used in Yemen by traditional healers for the treatment of malaria as well as other diseases, were collected from different localities of Yemen, dried and extracted with methanol and water successfully. The antiplasmodial activity of the extracts was evaluated against fresh clinical isolates of Plasmodium falciparum.

Increasing single and multi-antibiotic resistance in Shigella species isolated from shigellosis patients in Sana'a, Yemen.

Objective: The epidemiology and antibiotic susceptibility of Shigella species changes over time. Updated susceptibility knowledge is necessary for appropriate empirical antibiotic treatment. Thus, this research aimed to study these changes in 2 time periods with an interval of 10 years.

Seroprevalence of Helicobacter pylori among children in Sana'a, Yemen.

Background: Helicobacter pylori infection is primarily acquired in early childhood. Its transmission routes are debated. The aims of this study were to determine the seroprevalence of anti-H.