Could environmental exposure and climate change Be a key factor in the rising incidence of early onset colorectal cancer?

The emergence of early onset colorectal cancer (EOCRC) is believed to result from the complex interplay between external environmental factors and internal molecular processes. This review investigates the potential association between environmental exposure to chemicals and climate change and the increased incidence of EOCRC, focusing on their effects on gut microbiota (GM) dynamics. The manuscript explores the birth cohort effect, suggesting that individuals born after 1950 may be at higher risk of developing EOCRC due to cumulative environmental exposures.

Additive effects of microplastics on accumulation and toxicity of cadmium in male zebrafish.

Microplastics (MPs) have emerged as contaminants of concern because of their ubiquitous presence in almost all aquatic environments. The ecological effects of MPs are complex and depend on multiple factors including their age, size and the ecological matrix. There is an urgent need for multifactorial studies to elucidate their impacts.

Human and ecological risk assessment of heavy metals in different particle sizes of road dust in Muscat, Oman.

Heavy metal contamination of Hg, As, Cu, Cr, Zn, and Pb was investigated in three different fractions 45, 125, and 200 μm of road dust in Muscat, Oman. Dust samples were collected from three different traffic roads, viz. high, medium, and low based on traffic volume and then sieved individually before they analyzed using inductively coupled plasma optical emission spectrometry (ICP-OES).

Heavy metals levels in road dust from Muscat, Oman: relationship with traffic volumes, and ecological and health risk assessments.

Dust samples from roads classified based on traffic volumes (low, medium and high traffic) were collected from Muscat, Oman, and then analyzed for a dozen heavy metals. Their contents varied widely with mercury and iron, having the lowest and highest concentrations (0.59-0.

The influence of dissolved organic matter (DOM) on sodium regulation and nitrogenous waste excretion in the zebrafish (Danio rerio).

Dissolved organic matter (DOM) is both ubiquitous and diverse in composition in natural waters, but its effects on the branchial physiology of aquatic organisms have received little attention relative to other variables (e.g. pH, hardness, salinity, alkalinity).

The effect of dissolved organic matter (DOM) on sodium transport and nitrogenous waste excretion of the freshwater cladoceran (Daphnia magna) at circumneutral and low pH.

Dissolved organic matter (DOM), a heterogeneous substance found in all natural waters, has many documented abiotic roles, but recently, several possible direct influences of DOM on organism physiology have been reported. However, most studies have been carried out with a limited number of natural DOM isolates or were restricted to the use of commercial or artificial humic substances. We therefore employed three previously characterized, chemically-distinct natural DOMs, as well as a commercially available humic acid (Aldrich, AHA), at circumneutral (7-8) and acidic pH (~5), to examine DOM effects on whole-body Na(+) concentration, unidirectional influx and efflux rates of Na(+), and ammonia and urea excretion rates in Daphnia magna.

Characterization of freshwater natural dissolved organic matter (DOM): mechanistic explanations for protective effects against metal toxicity and direct effects on organisms.

Dissolved organic matter (DOM) exerts direct and indirect influences on aquatic organisms. In order to better understand how DOM causes these effects, potentiometric titration was carried out for a wide range of autochthonous and terrigenous freshwater DOM isolates. The isolates were previously characterized by absorbance and fluorescence spectroscopy.

Evaluating the ameliorative effect of natural dissolved organic matter (DOM) quality on copper toxicity to Daphnia magna: improving the BLM.

Various quality predictors of seven different natural dissolved organic matter (DOM) and humic substances were evaluated for their influence on protection of Daphnia magna neonates against copper (Cu) toxicity. Protection was examined at 3 and 6 mg l(-1) of dissolved organic carbon (DOC) of each DOM isolate added to moderately hard, dechlorinated water. Other water chemistry parameters (pH, concentrations of DOC, calcium, magnesium and sodium) were kept relatively constant.

Physicochemical and spectroscopic properties of natural organic matter (NOM) from various sources and implications for ameliorative effects on metal toxicity to aquatic biota.

Natural organic matter (NOM), expressed as dissolved organic carbon (DOC in mgCL(-1)), is an ubiquitous complexing agent in natural waters, and is now recognized as an important factor mitigating waterborne metal toxicity. However, the magnitude of the protective effect, judged by toxicity measures (e.g.

Evaluating mercury biomagnification in fish from a tropical marine environment using stable isotopes (delta13C and delta15N).

Concentrations of total mercury (T-Hg) and methylmercury (MeHg) were measured in zooplankton and 13 fish species from a coastal food web of the Gulf of Oman, an arm of the Arabian Sea between Oman and Iran. Stable isotope ratios (delta13C and delta15N) also were determined to track mercury biomagnification. The average concentration of T-Hg in zooplankton was 21 +/- 8.

Photochemical reduction and reoxidation of aqueous mercuric chloride in the presence of ferrioxalate and air.

In this study, ferric oxalate is used to represent the photosensitive Fe(III) complexes as well as the diacid compounds which are at significant concentrations in cloud and rain droplets. Because of the common carboxylate functional group; ferric oxalate is also used as a model to represent humic substances found in natural water. UVA irradiation of aqueous acidic mercuric chloride (pH 1-4) in the presence of an excess of ferrioxalate results in partial reduction of the mercuric ion to elemental mercury.