Publications by authors named "Hasin Afzal Ahmed"
Shifting-and-Scaling Correlation Based Biclustering Algorithm.
IEEE/ACM Trans Comput Biol Bioinform
March 2016
Article Synopsis
- The existence of various correlations among biologically significant genes complicates gene expression data analysis, prompting researchers to explore beyond traditional methods.
- The study introduces a new correlation measure called Shifting and Scaling Similarity (SSSim), which helps identify highly correlated gene pairs in expression data.
- An innovative technique, the Intensive Correlation Search (ICS) biclustering algorithm, utilizes SSSim to reveal functionally significant groups of genes, demonstrating good performance with benchmark datasets.
Construction of co-expression network and extraction of network modules have been an appealing area of bioinformatics research. This article presents a co-expression network construction and a biologically relevant network module extraction technique based on fuzzy set theoretic approach. The technique is able to handle both positive and negative correlations among genes.
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