Background: Semaglutide, a glucagon-like peptide-1, is an effective antidiabetic drug promoting weight loss and providing cardiovascular protection. The original trials did not include participants from Saudi Arabia; hence, the study's findings are expected to be useful.
Objectives: Explore the efficacy, safety, and favorable effects of once-weekly subcutaneous semaglutide (1 mg) in patients with type 2 diabetes and those who received it as an off-license prescription without having diabetes.
Quality detection is critical in the development of prepared dishes, with distributional uniformity playing a significant role. This study used hyperspectral imaging (HSI) and Moran's I to quantify distributional uniformity, employing pizza as case. Pizza ingredients' spectra were collected, pre-processed with Detrended Fluctuation Analysis (DFA), Savitzky-Golay (SG) and Standard Normal Variate (SNV), and down-scaled with Principal Component Analysis (PCA).
View Article and Find Full Text PDFObjectives: Glaucoma is a leading cause of permanent blindness. Despite therapeutic advancements, glaucoma management remains challenging due to limitations of conventional drug delivery, primarily topical eye drops, resulting in suboptimal outcomes and a global surge in cases. To address these issues, liposomal drug delivery has emerged as a promising approach.
View Article and Find Full Text PDFBackground: Ophthalmic care is a fundamental component of patient care, encompassing a range of interventions such as basic eye hygiene and medication administration, through to advanced skills in assessment and diagnostics.
Aim: To explore what is known about ophthalmic content in nurse education, training and curricula and identify advanced nursing skills necessary for competence in ophthalmic care.
Design: This scoping review was informed by Joanna Briggs Institute (JBI) methodology and is reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews Checklist (PRISMA-SrC).
L. is a valuable multipurpose tree species widely planted for centuries due to its high medicinal value and antifungal, antiviral, antidepressant, and anti-inflammatory properties in the food industry. However, its cultivation is hindered by production constraints such as the unavailability of planting material and the inadequate number of high-yielding clones.
View Article and Find Full Text PDFThere are limited reports on the impact of prosthesis-patient mismatch (PPM) on the regression of left ventricular hypertrophy (LVH) after transcatheter aortic valve replacement (TAVR). We compared the relative effects of supra-annular, self-expanding (SE) versus intra-annular, balloon-expandable (BE) prostheses on TAVR LVH regression. Regression of left ventricular mass index (LVMi) was evaluated in 168 consecutive TAVR patients, including 60 treated with SE valves (Evolut series) and 108 treated with BE valves (Sapien 3).
View Article and Find Full Text PDFObjective: The goal of the present research was to evaluate the effectiveness of physical exercise intervention in enhancing psychological well-being and decreasing symptoms of depression among college students, adopting a systematic review and meta-analysis.
Methodology: The study was performed by searching four databases (PubMed, Embase, Web of Science, and the Cochrane Library) to determine randomized controlled trials (RCTs) exploring the impacts of physical exercise therapies among college students with symptoms of depression. The sequential execution of a meta-analyses, subgroup analyses, and publication bias analyses was accomplished utilizing the software package RevMan version 5.
Objective: We conducted a systematic review of all available evidence on the feasibility and safety of minimally invasive coronary artery bypass grafting (MICS CABG) in patients with multivessel coronary artery disease (CAD).
Methods: A systematic literature search in PubMed, MEDLINE via Ovid, Embase, Scopus, and Web of Science was performed to identify all relevant studies evaluating outcomes of MICS CABG among patients with multivessel CAD and including at least 15 patients with no restriction on the publication date.
Results: A total of 881 studies were identified, of which 26 studies met the eligibility criteria.
In order to implement the fifth generation (5G) communication system for a large number of users, the governments of many countries nominated the low 5G frequency band between 3.3 and 4.3 GHz.
View Article and Find Full Text PDFFood Chem
December 2024
Profiling of metabolites that contribute to the taste and odor of fruit products is important to produce the desired products. In this study, volatile and non-volatile compounds were analyzed using SPME/GC-MS and UHPLC-Q-Exactive-orbitrap-MS/MS, respectively. A total of 59 volatiles (including alcohols, aldehydes, acids, terpenes, ketones, phenols, and hydrocarbons et al.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2024
Air pollutants generated from volatile toxic chemicals pose significant public health concerns. Density functional theory (DFT) computations were used in this research to explore the efficiency and mechanism of harmful gas sensing over the reduced graphene oxide-polypyrrole (rGO-PPy) composite. Volatile molecule sensing was investigated for the NH, HCO, CHOH, and CHOH gas molecules over three PPy orientations on the rGO substrate.
View Article and Find Full Text PDFBackground: The primary cause of maternal and fetal mortality due to hypertensive disorders in pregnancy is delays in accessing healthcare services. These delays are often attributed to insufficient knowledge, attitudes at the time of diagnosis, and a lack of awareness regarding the condition, including its critical warning signs and symptoms.
Aim: To evaluate pregnant women's initial knowledge and attitudes upon receiving their first diagnosis of hypertensive disorders of pregnancy.
Post-stroke cognitive impairment (PSCI) is a common decline in cognitive abilities that occurs within 3 months after a stroke. During recovery, stroke survivors often experience varying degrees of cognitive decline, with some patients experiencing permanent cognitive deficits. Thus, it is crucial to prioritise recovery and rehabilitation after a stroke to promote optimal protection of and improvement in cognitive function.
View Article and Find Full Text PDFPrevious reports on the impact of preexisting atrial fibrillation (AF) on clinical outcomes after transcatheter aortic valve implantation (TAVI) have presented limited data on the relative impact of paroxysmal versus persistent AF subtypes. We compared in-hospital, 1-year, and late clinical outcomes in 1,098 patients who underwent TAVI with preoperative AF (556 paroxysmal, 542 persistent) versus 1,787 patients without AF. The propensity-matched cohorts with AF (n = 643) and without AF (n = 686) did not differ with respect to baseline clinical characteristics, operative technique, or in-hospital TAVI complications.
View Article and Find Full Text PDFBackground: Mounting research suggests that artificial intelligence (AI) is one of the innovations that aid in the patient's diagnosis and treatment, but unfortunately limited research has been conducted in this regard in the Kingdom of Saudi Arabia (KSA). Hence, this study aimed to assess the level of knowledge and awareness of AI among faculty members and medicine students in one of the premier medical colleges in KSA.
Methods: A cross-sectional descriptive study was conducted at Batterjee Medical College (BMC), Jeddah (KSA), from November 2022 to April 2023.
This study aimed to develop an eco-friendly active biogenic nanocomposite film through the complexation of silver nanoparticles (AgNPs), berry wax (BYW), and chitosan (CT) for maintiaing rabbit functional meat freshness. AgNPs were synthesized using Chinese medicinal paeoniaceae petal extract, and they were loaded at various concentrations (0.5 %, 0.
View Article and Find Full Text PDFRotating Polarization Wave (RPW) is a novel Low Power Wide Area Networks (LPWAN) technology for robust connectivity and extended coverage area as compared to other LPWAN technologies such as LoRa and Sigfox when no error detection and correction is employed. Since, IoT and Machine-to-Machine (M2M) communication demand high reliability, RPW with error correction can significantly enhance the communication reliability for critical IoT and M2M applications. Therefore, this study investigates the performance of RPW with single bit error detection and correction using Hamming codes to avoid substantial overhead.
View Article and Find Full Text PDFIntroduction: Failure of anterior cruciate ligament (ACL) reconstructive surgery often presents alongside progressive mono-compartment tibiofemoral arthritis. Total knee arthroplasty (TKA) is the conventional treatment option for this scenario but is associated with high levels of dissatisfaction amongst this younger cohort.
Case Report: This case report outlines a 39-year-old male patient, who underwent revision ACL reconstruction plus a medial unicompartmental knee arthroplasty (UKA) replacement as a single-stage procedure.
Background: Simulated self-practice using simulation models could improve fine motor skills and self confidence in surgical trainees.
Aims: The purpose of this study is to evaluate on self-reported confidence level in cardiothoracic surgical trainees by using surgical simulation models.
Methods: We conducted a cross-sectional study on all surgeons (n=10) involved in MIS simulation training.
The current study entails the encapsulation validity to enclose naturally occurring food preservatives, such as cinnamon essential oil (CM), within various wall materials. This approach has demonstrated enhanced encapsulated compounds' stability, efficiency, and bioactivity. The base carrier system consisted of a solid lipid (Berry wax, RW) individually blended with whey protein (WYN), maltodextrin (MDN), and gum Arabic (GMC) as wall materials.
View Article and Find Full Text PDFContext: The prevalence of depression among teenagers is a significant issue worldwide, which calls for a thorough investigation of non-drug treatments. This expedited evaluation examines 24 specifically chosen studies to clarify the correlation between physical activity depression symptoms in teenagers, undertaken following PRISMA principles.
Methods: A wide range of research methods, including longitudinal studies, surveys, and cross-sectional analyses, were used in different nations to understand the intricate relationship between physical activity, sedentary behaviours, and depression symptoms.
A 39-year-old man presented for mechanical thrombectomy after receiving systemic tissue plasminogen activator (tPA) for a basilar artery occlusion. The anesthesiology team was initially unable to intubate the patient due to oropharyngeal bleeding and a large epiglottis. Two-handed, 2-provider mask ventilation with an oral airway proved difficult.
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