An Unexpected Response of Orbital Retinoblastoma to Inconsistent Systemic Chemotherapy Alone.

Introduction: A 16-month-old girl presented with bilateral germline retinoblastoma, with advanced retinoblastoma in the right eye and severe orbital retinoblastoma in the left eye. Patients typically receive treatment with the multimodal protocol consisting of chemotherapy, surgery, and radiotherapy, which has improved survival.

Case Presentation: Our patient elected for medical management with systemic chemotherapy instead of enucleation or exenteration.

Malignant Dendritic Cell Sarcomas in the Skin: 2 Cases of Rare Sarcoma Subtypes With Literature Review.

Interdigitating dendritic cell sarcoma is a rare, aggressive hematological malignancy primarily originating in lymph nodes, with only 10 reported cases presenting in the skin (primary cutaneous interdigitating dendritic cell sarcoma). Past presentations showed erythematous nodules on the proximal extremities, back, or face. Morphologically, these neoplasms are similar to melanomas and other dendritic cell (DC) tumors, making their diagnosis difficult.

Dogs Licks Are Not Benign: Pasturella Multocida Bacteremia From Household Dog.

is a gram-negative coccobacilli commonly colonized in the oral, nasopharyngeal, and upper respiratory tracts of animals. Infections due to range in severity, and symptoms largely depend on underlying immune status and co-morbid conditions. Widely known, the transmission of is commonly thought to occur through biting and skin breakage alone.

Ophthalmic manifestations of Lamb-Shaffer syndrome: a case presentation and literature review.

Lamb-Shaffer syndrome, caused by haploinsufficiency of SOX5, leads to a unique constellation of dysmorphic features and intellectual delay. The SOX5 family of proteins plays an integral role in neuronal development. We present the clinical traits of an 11-year-old boy with Lamb-Shaffer syndrome and highlight the ocular findings of the syndrome reported thus far in the literature.