The indicator of hypoxia in acute leukemia: Ischemia-modified albumin.

Background: Hypoxia plays an important role in the development and progression of hematologic malignancies.

Objective: This study was intended to investigate the effectiveness of ischemia-modified albumin (IMA) for demonstrating hypoxia in patients with acute leukemia.

Methods: Blood specimens were collected from 132 subjects (44 acute leukemia patients, 40 iron deficiency anemia (IDA) patients and 48 healthy controls).