Review of the Current Literature and Our Experience on the Value of OCT-angiography in White Dot Syndromes.

Purpose: To describe the application of OCT-A in various posterior uveitis disorders in our experience and to compare it with the available literature.

Methods: Eighteen eyes with the diagnoses of multifocal choroiditis (MFC), multifocal placoid pigment epitheliopathy (APMPPE), multiple evanescent white dot syndrome (MEWDS), tuberculous serpiginous-like choroiditis (SLC), serpiginous choroiditis (SC), and birdshot chorioretinopathy (BSCR) were studied.

Results: We found flow void of the choriocapillaris in patients with APMPPE, SC, MFC, BSCR, and in SLC.

Upper Airway Stimulation Response in Older Adults with Moderate to Severe Obstructive Sleep Apnea.

Objective: To evaluate the impact of age on safety, efficacy, and usage of upper airway stimulation (UAS).

Study Design: Multicenter observational study.

Setting: Thirteen US hospitals and 3 German hospitals.

Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Upper airway stimulation (UAS) has been shown to reduce severity of obstructive sleep apnoea. The aim of this study was to identify predictors of UAS therapy response in an international multicentre registry.Patients who underwent UAS implantation in the United States and Germany were enrolled in an observational registry.

The effect of alpha blockade on iontophoresis-induced ocular shedding of latent HSV-1 W in different host animals.

Previous studies demonstrated that non-specific beta blockade promoted ocular shedding of latent HSV-1 in the mouse and rabbit iontophoresis models. The present study examined the effect of topical alpha blockers, thymoxamine and corynanthine, on reactivation and induced ocular shedding of latent HSV-1 W in different host animals. Latent trigeminal ganglionic infection was established in Balb/c mice and New Zealand rabbits following corneal inoculation with HSV-1 W strain, and later confirmed by co-cultivation.

Timolol promotes reactivation of latent HSV-1 in the mouse iontophoresis model.

The present study examined the effect of topical timolol, a nonspecific beta 1 and beta 2 blocker on reactivation and ocular shedding of latent HSV-1 in an improved mouse iontophoresis model. Latent trigeminal ganglionic infection was established in Balb/C mice following inoculation by corneal scarification with HSV-1 W strain, a clinical isolate, and confirmed by co-cultivation. On day 30, postinfection (pi), the mice were divided into two groups, and treatment begun with coded eye drops (timolol 0.

Incidence of Moraxella conjunctival infection.

Thirty-three cases of Moraxella conjunctival infection, many incorrectly diagnosed as Chlamydia, epidemic keratoconjunctivitis, and herpes simplex infections, were confirmed by bacterial cultures and Giemsa staining during a one-year period. Although Moraxella conjunctivitis is associated with adolescent girls, 13 of our 27 female patients with Moraxella infection (48%) were 20 years or older. Although corneal involvement, preauricular adenopathy, and ocular nodules are not classically associated with Moraxella conjunctivitis, these symptoms were present in 15 cases (45%).

Review of cyanoacrylate tissue glues with emphasis on their otorhinolaryngological applications.

Cyanoacrylates were first synthesized by Ardis in 1949. However, it was not until Coover in 1959 discovered their adhesive properties that an interest arose in using these substances in surgical procedures. Over the past two decades the use of cyanoacrylates has been varied and widespread among the surgical specialties.