Publications by authors named "Harvey K Kamboyi"
Background: The inappropriate use of antibiotics in hospitals contributes to the development and spread of antimicrobial resistance (AMR). This study evaluated the prevalence of antibiotic use and adherence to the World Health Organization (WHO) Access, Watch and Reserve (AWaRe) classification of antibiotics across 16 hospitals in Zambia.
Methods: A descriptive, cross-sectional study employing the WHO Point Prevalence Survey (PPS) methodology and WHO AWaRe classification of antibiotics was conducted among inpatients across 16 hospitals in December 2023, Zambia.
Background: Bacillus cereus is a Gram-positive, spore-forming bacterium that produces a spectrum of effectors integral to bacterial niche adaptation and the development of various infections. Among those is EsxA, whose secretion depends on the EssC component of the type VII secretion system (T7SS). EsxA's roles within the bacterial cell are poorly understood, although postulations indicate that it may be involved in sporulation.
View Article and Find Full Text PDFBackground: Bacillus anthracis is a highly pathogenic bacterium that can cause lethal infection in animals and humans, making it a significant concern as a pathogen and biological agent. Consequently, accurate diagnosis of B. anthracis is critically important for public health.
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- * A survey of poultry farmers in ten Zambian districts revealed that medium-/small-scale farmers used more antimicrobials but had fewer prescriptions compared to commercial farmers.
- * Testing of 150 poultry isolates showed high resistance rates, especially to ampicillin and tetracycline, with the presence of extended-spectrum β-lactamase (ESBL) genes indicating significant AMR concerns in the poultry sector.
Antiretroviral treatment failure has emerged as a challenge in the management of pediatric human immunodeficiency virus (HIV) patients, especially in resource-limited countries despite accessibility to Highly Active Antiretroviral Therapy (HAART). A systematic review and meta-analysis was conducted to synthesize virological failure (VF) prevalence and ascertain its predictors in children in sub-Saharan Africa. An electronic database search strategy was conducted from January to September 2021 on PubMed, EMBASE, SCOPUS, HINARI, and CINAHL.
View Article and Find Full Text PDFObjective: To explore the health professionals' and community members' perspectives on the factors influencing transmission of the novel COVID-19 in Zambia.
Design: An exploratory qualitative study using in-depth interviews as data collection technique.
Setting: Four primary healthcare facilities and local communities of Lusaka city and Chirundu international border town under Lusaka province, Zambia.
Article Synopsis
- Anthrax is becoming a serious threat in Zambia, affecting humans, livestock, and wildlife, which is disrupting eco-tourism and destabilizing wildlife sanctuaries.
- A study aimed to map the distribution of anthrax and identify ecological factors contributing to its spread, using samples and questionnaires from rural areas.
- The study found that inadequate carcass disposal and limited veterinary services significantly increase the risk of anthrax outbreaks, with 78.7% of cases occurring in regions with poor access to veterinary care.