Dissecting structure and function of the monovalent cation/H antiporters Mdm38 and Ylh47 in .

Unlabelled: Mdm38 and Ylh47 are homologs of the Ca/H antiporter Letm1, a candidate gene for seizures associated with Wolf-Hirschhorn syndrome in humans. Mdm38 is important for K/H exchange across the inner mitochondrial membrane and contributes to membrane potential formation and mitochondrial protein translation. Ylh47 also localizes to the inner mitochondrial membrane.