- The study aimed to evaluate how fetal fractions in non-invasive prenatal testing (NIPT) can help predict pregnancy complications like gestational diabetes and hypertension by comparing results from different gestational ages and maternal characteristics.
- Conducted as a multicenter cohort study, it analyzed data from 5,582 women with negative NIPT results to explore the links between fetal fractions and pregnancy outcomes such as miscarriages and complications.
- Results indicated that women who developed hypertensive disorders tended to have lower fetal fractions early in pregnancy, but using this marker to predict such conditions proved challenging.