5--Carboxyimino-6-aminopyrimidine-2,4(3)-dione, a novel indicator for hypochlorite formation.

Uric acid is an adequate and endogenous probe for identifying reactive oxygen or nitrogen species generated because its oxidation products are specific to reacted reactive oxygen or nitrogen species. Recently, we identified 5--carboxyimino-6--chloroaminopyrimidine-2,4(3)-dione as a hypochlorite-specific oxidation product. 5--carboxyimino-6--chloroaminopyrimidine-2,4(3)-dione was anticipated to be a biomarker for hypochlorite production .