This study investigated the effects of perioperative inhaled tiotropium on patients with COPD undergoing esophagectomy, focusing on pneumonia risk and pulmonary function.
32 patients were randomly assigned to either a control group with conventional management or an intervention group receiving tiotropium inhalation before and after their surgery.
While the incidence of pneumonia was similar in both groups, the patients using tiotropium showed improved pulmonary function and exercise capacity, leading to less deterioration post-surgery.
* The EPITOPE study evaluates the impact of inhaled tiotropium, a medication used for COPD management, in preventing postoperative pneumonia in COPD patients undergoing esophageal cancer surgery.
* This randomized controlled trial will measure pneumonia incidence and other complications within 30 days post-surgery, assessing respiratory function and overall health outcomes before and after the intervention.