Publications by authors named "Hart Mann Alain Youbi Mambou"

Malaria is a deadly parasitic disease caused a by protozoan parasite of the genus plasmodium. The challenges facing by chemotherapy and vector control couple with the lack of vaccine against malaria necessitate an urgent need for the development of alternative treatment regimens to combat this disease. One possible antimalarial treatment regimen is the use of probiotic bacteria as dietary supplements.

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Article Synopsis
  • The study investigated the effects of active fractions from root barks on convulsions in mouse models induced by pentylenetetrazole, focusing on their anticonvulsant, antioxidant, and neuroprotective properties.
  • AFAD treatment significantly reduced the frequency and duration of seizures and improved overall seizure scores in mice experiencing induced seizures.
  • Results indicated that AFAD helped restore the balance of oxidants and antioxidants, increased brain GABA levels, and reduced neuronal cell loss, suggesting its potential as a treatment for epilepsy.
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