Publications by authors named "Harsheen K Manaise"
Background/aim: Surgery is the cornerstone of treatment for papillary thyroid cancer (PTC), yet some patients refuse surgery, which may impact their survival outcomes. Understanding factors associated with surgery refusal could inform interventions to improve acceptance of recommended care.
Patients And Methods: This retrospective cohort study evaluated the impact of surgery refusal on overall survival (OS) and identified associated demographic and clinical factors using data on patients with PTC from the National Cancer Database from 2004 to 2019.
This editorial commented on an article in the titled "Risks of Reactivation of Hepatitis B Virus in Oncological Patients Using Tyrosine Kinase-Inhibitors: Case Report and Literature Analysis" by Colapietro . In this editorial, we focused on providing a more comprehensive exploration of hepatitis B virus reactivation (HBVr) associated with the usage of tyrosine kinase inhibitors (TKIs). It includes insights into the mechanisms underlying HBV reactivation, the temporal relationship between TKIs and HBV reactivation, and preventive measures.
View Article and Find Full Text PDFBackground: This study investigated demographic and socioeconomic factors contributing to disparities in the time to treatment for rectal cancer. Subgroup analysis based on age < 50 and ≥ 50 was performed to identify differences in time to treatment among young adults (age < 50) compared to older adults with rectal cancer.
Methods: An analysis was performed using data from the National Cancer Database, spanning from 2004 to 2019.
Histology is an important predictor of the behavior of breast cancer. We aim to study the impact of histology on the overall survival (OS) of breast cancer patients. We studied 11,085 breast cancer patients diagnosed with T1-T2 tumors, clinically node-negative and non-metastatic, from 2004 to 2019 included in the National Cancer Database.
View Article and Find Full Text PDFWe aimed to review the molecular characteristics of metastatic melanoma and the role of surgery in metastasectomy for metastatic melanoma. We performed a systematic literature search on PubMed to identify relevant studies focusing on several mutations, including NRAS, BRAF, NF1, MITF, PTEN, TP53, CDKN2A, TERT, TMB, EGFR, and c-KIT. This was performed in the context of metastatic melanoma and the role of metastasectomy in the metastatic melanoma population.
View Article and Find Full Text PDFArticle Synopsis
- Gastric cancer is a significant health issue, ranking as the 5th most common cancer globally and contributing to a high number of deaths, with various treatments available but often delayed due to socio-demographic disparities.
- A study from 2004 to 2019 analyzed data from the National Cancer Database, revealing significant delays in treatment based on age, sex, race, and socioeconomic status, with specific groups experiencing notably longer wait times.
- Identifying these disparities is essential for creating strategies to ensure timely treatment for gastric cancer patients, and future research should focus on updated data and prospective study designs to better address these issues.
Background/aim: This study aimed to investigate the demographic and socioeconomic factors associated with disparities in the time-to-treatment for melanoma.
Patients And Methods: We conducted an analysis of patients with melanoma from 2004 to 2019 using the National Cancer Database. Time intervals from diagnosis to surgery, radiation, and chemotherapy were compared based on age, sex, race, and socioeconomic status.
Background/aim: Skin cancer is the most common cancer worldwide. This study aimed to identify factors contributing to the disparities in skin cancer treatment.
Patients And Methods: Data from The National Cancer Database (NCDB) spanning 2004 to 2019 were utilized.
Background/aim: Pancreatic cancer has a high mortality rate and timely treatment is imperative for favorable patient outcomes. This retrospective study aimed to identify disparities in time to treatment for pancreatic cancer based on sociodemographic factors.
Patients And Methods: The study used the National Cancer Database from 2004 to 2019.
Article Synopsis
- The study aimed to explore how socioeconomic and demographic factors affect delays in treatment for thyroid cancer patients, using data from the National Cancer Database spanning 2004 to 2019.
- It included a vast sample of over 434,000 thyroid cancer patients, analyzing wait times based on factors such as age, race, sex, location, and socioeconomic status (SES).
- Results showed significant disparities, with Hispanic patients and those who are uninsured or at academic facilities facing notably longer wait times for various treatments, highlighting the need for further investigation to address these inequities.