Publications by authors named "Harsh P Patel"
Article Synopsis
- Cardiomyopathy (CDM) during pregnancy significantly impacts maternal health, with serious risks leading to morbidity and mortality.
- Analysis of delivery hospitalizations from 2005-2020 showed that peripartum cardiomyopathy (PPCM) represented the majority of cases, followed closely by dilated cardiomyopathy (DCM), while hypertrophic (HCM) and restrictive cardiomyopathy (RCM) were less common.
- PPCM was linked to the highest in-hospital mortality and adverse events, though its prevalence has decreased over time, while DCM and HCM rates have increased, highlighting a need for more research in this area.
A Case of McLeod's Syndrome Presenting with Severe Decompensated Heart Failure.
Methodist Debakey Cardiovasc J
September 2023
Article Synopsis
- - McLeod's syndrome (MLS) is an X-linked genetic disorder linked to the XK gene that results in neurological issues and heart problems, specifically cardiomyopathy.
- - The case discussed involves a 44-year-old White male experiencing a severe heart failure flare-up due to MLS.
- - Treatment included following standard medical guidelines and using an implantable cardioverter defibrillator, leading to improvement in his heart's ejection fraction.
Impact of Atrial Fibrillation on Outcomes in Patients Hospitalized With Nontraumatic Intracerebral Hemorrhage.
Mayo Clin Proc Innov Qual Outcomes
August 2023
Objective: To assess the effect of atrial fibrillation (AF) on outcomes in hospitalizations for non-traumatic intracerebral hemorrhage (ICH).
Patients And Methods: We queried the National Inpatient Sample database between January 1, 2016, and December 31, 2019, to identify hospitalizations with an index diagnosis of non-traumatic ICH using ICD-10 code I61. The cohort was divided into patients with and without AF.
Article Synopsis
- * A study analyzing data from 2016 to 2019 found that out of nearly 48,000 CA procedures, cancer patients had higher in-hospital mortality, lower chances of being discharged home, and increased risks of complications like major bleeding and pulmonary embolism.
- * The findings suggest that while CA can be effective, cancer patients face notable risks, highlighting the need for larger studies to confirm these results and explore safer treatment options.
Background: Influenza disproportionately affects individuals with underlying comorbidities. Long-term follow-up studies have shown that patients with cancer with influenza have higher mortality. However, very little is known about the in-hospital mortality and cardiovascular outcomes of influenza infection in cancer hospitalisations.
View Article and Find Full Text PDFHigh degree atrioventricular block (HDAVB) is an uncommon complication of non-ST-segment elevation myocardial infarction (NSTEMI) that frequently necessitates pacemaker implantation. This contemporary analysis compares need for pacemaker implantation based on the timing of intervention in acute NSTEMI complicated by HDAVB. We used 2016-2017 National Inpatient Sample database to identify admissions with NSTEMI and HDAVB.
View Article and Find Full Text PDFBackground: Influenza disproportionately affects individuals with underlying comorbidities. Long-term follow-up studies have shown that patients with cancer with influenza have higher mortality. However, very little is known about the in-hospital mortality and cardiovascular outcomes of influenza infection in cancer hospitalisations.
View Article and Find Full Text PDFBackground: The use of cannabis has massively increased among younger patients due to increasing legalization and availability.
Methods: We performed a retrospective nationwide study using the Nationwide inpatient sample (NIS) database to analyze the trends of acute myocardial infarction (AMI) in young cannabis users and related outcomes among patients aged 18-49 years from 2007 to 2018, using ICD-9 and ICD-10 codes.
Results: Out of 819,175 hospitalizations, 230,497 (28%) admissions reported using cannabis.
One-year outcomes of catheter ablation for atrial fibrillation in young patients.
BMC Cardiovasc Disord
February 2023
Background: Atrial fibrillation (AF) is relatively less frequent in younger patients (age < 50). Recently, studies have suggested that early restoration of sinus rhythm may lead to improved outcomes compared with rate control, however the efficacy of catheter ablation for AF in young is scarce.
Methods: We included all hospitalized patients between 18 and 50 years with a diagnosis of AF from the Nationwide Readmission Database 2016-2017 from the Healthcare Cost and Utilization Project.
Cardiogenic shock (CS) is significant cause of mortality. The use of mechanical circulatory support (MCS) in patients with non-acute myocardial infarction (Non-AMI) CS is lacking. We inquired data regarding the trends and outcomes early vs late initiation of MCS in non-AMI CS.
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- Research on endovascular treatment (EVT) for acute limb ischemia (ALI) in patients with advanced chronic kidney disease (CKD) and end-stage renal disease (ESRD) is limited.
- A study analyzed hospitalizations from 2015 to 2017, revealing that patients with advanced CKD (stages III-V) faced significantly higher in-hospital mortality and complications compared to those without CKD.
- The findings highlight that patients with severe CKD and ESRD have worse health outcomes and increased healthcare costs after EVT for ALI, indicating the need for better treatment guidelines for these patients.
Racial disparities in ventricular tachycardia in young adults: analysis of national trends.
J Interv Card Electrophysiol
January 2023
Article Synopsis
- The prevalence of hospitalizations for ventricular tachycardia (VT) in young adults under 45 years is increasing, with significant rises in all-cause mortality rates and cardiac arrest incidents over different four-year periods from 2005 to 2018.
- Data was analyzed from over 5 million hospitalizations, revealing a concerning trend in both the number of young adults admitted with VT and associated economic burdens, such as increased hospital costs.
- The study found that while the average age of those hospitalized remained relatively stable, the demographic consistently showed a higher percentage of males and White individuals, highlighting potential disparities in risk factors related to race and gender.
Article Synopsis
- The study compared outcomes of patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) and complex coronary disease who underwent either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).
- No significant differences in major cardiac adverse events (MACE) or survival rates were found between PCI and CABG after 30 days.
- However, during long-term follow-up, PCI was linked to a higher risk of MACE compared to CABG, although both procedures had similar rates of stroke and all-cause mortality.
Article Synopsis
- * A systematic review of 15 studies involving 8,731 patients found gastrointestinal bleeding rates of 3.0% in randomized controlled trials (RCTs) and 1.9% in observational studies.
- * RCTs showed higher rates of gastrointestinal bleeding than observational studies, contributing to improved understanding of guidelines and patient management for TAVR procedures.
Major bleeding has been identified as one of the most common complications after transcatheter aortic valve implantation (TAVI) with some suffering gastrointestinal bleeding (GIB). This study aimed at assessing the incidence and predictors of GIB after TAVI in the United States. We performed a retrospective analysis of data from the National Inpatient Sample database from 2011 to 2018.
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- Multiple studies show that drug-eluting stents (DES) are better than bare-metal stents (BMS) for treating infrapopliteal chronic limb-threatening ischemia (CLTI), but real-world data on their usage is limited.
- In a study using the Nationwide Readmission Database, 58.1% of 1,817 patients used DES, with higher usage in teaching and larger hospitals, but this trend was stable over 2016-2017.
- DES usage was linked to a significantly lower rate of major amputations and needed limb revascularization compared to BMS, indicating their efficacy yet highlighting their underutilization in practice.
Article Synopsis
- Atrial arrhythmias frequently occur in patients with alcohol withdrawal syndrome (AWS) and lead to increased hospitalization rates.
- A large-scale study analyzed data from over 1.5 million hospitalizations related to AWS, revealing that 9.72% of these patients had arrhythmias, which significantly impacted their health outcomes.
- Patients with AWS and arrhythmias had higher in-hospital mortality, increased risks of complications (like heart failure and kidney injury), longer hospital stays, and greater treatment costs compared to those without arrhythmias.
Background: Cardiovascular implantable electronic device (CIED) infections are associated with increased mortality and morbidity.
Objective: This study sought to evaluate the impact of early vs delayed transvenous lead removal (TLR) on in-hospital mortality and outcomes in patients with CIED infection.
Methods: Using the nationally representative, all payer, Nationwide Readmissions Database, we evaluated patients undergoing TLR for CIED infection between January 1, 2016, and December 31, 2018.