Publications by authors named "Harry Sivakumar"

Article Synopsis
  • A study was conducted to evaluate the impact of epidural analgesia on quality outcomes in pediatric patients undergoing heart and lung transplant surgery.
  • Data from 62 patients over 17 years showed that those with epidural analgesia had a shorter median hospital stay and reduced need for postoperative opioids, but no significant differences in overall survival or other major outcomes.
  • The findings suggest a potential benefit of epidural analgesia, but further research with larger sample sizes is necessary to draw more definitive conclusions.
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Preoperative cardiopulmonary exercise testing (CPET) provides an objective assessment of aerobic fitness in patients undergoing surgery. While peak oxygen uptake during exercise (VO2peak) and anaerobic threshold have demonstrated a moderate correlation with the development of complications following esophagectomy, no clinically useful threshold values have been defined. By pooling patient level data from existing studies, we aimed to define optimal thresholds for preoperative CPET parameters to predict patients at high risk of postoperative complications.

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Introduction: Cardiopulmonary exercise testing (CPET) is an objective method of assessing functional capacity to meet the metabolic demands of surgery and has been adopted as a preoperative risk-stratification tool for patients undergoing major procedures. The two main measures are the peak rate of oxygen uptake during exercise ([Formula: see text]Opeak) and anaerobic threshold (AT), the point at which anaerobic metabolism exceeds aerobic metabolism during exercise. This systematic review and meta-analysis evaluates the predictive value of CPET for patients undergoing oesophagectomy.

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