Publications by authors named "Harry Severance"

Background: The rate-limiting step in STEMI diagnosis often is the availability of a 12-lead electrocardiogram (ECG) and its interpretation. The potential may exist to speed the availability of 12-lead ECG information by using commonly available mobile technologies. We sought to test whether combining serial smartphone single-lead ECGs to create a virtual 12-lead ECG can accurately diagnose STEMI.

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Article Synopsis
  • Rapid diagnosis and access to reperfusion therapy are crucial for optimal outcomes in STEMI patients.
  • The ST LEUIS study aims to validate a smartphone ECG app against traditional 12-lead ECGs for detecting STEMI in chest pain patients.
  • Conducted over 12 months at five institutions, the study plans to enroll 300 patients to assess the app's diagnostic accuracy.
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Background: Diagnostic testing in the care of patients newly presenting with symptoms suggestive of coronary artery disease may influence risk factor management, independent of test type or test results. However, little is known about changes in medications and lifestyle after anatomical or functional testing.

Methods And Results: We examined what factors influenced preventive medical therapy and lifestyle practices at 60 days among 10 003 symptomatic patients (53% women; mean age 61 years) randomly assigned to anatomical testing with coronary computed tomographic angiography or functional testing (NCT01174550).

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Objectives: The effect of emergency medicine (EM) residents on the clinical efficiency of attending physicians is controversial. The authors hypothesized that implementing a new EM residency program would result in an increase in relative value units (RVUs) generated per hour by attending physicians and decrease staffing requirements.

Methods: This was a retrospective observational analysis of an emergency department before, during, and after the establishment of a new EM residency program.

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Although the prognosis of ambulatory heart failure (HF) has improved dramatically there have been few advances in the management of acute HF (AHF). Despite regional differences in patient characteristics, background therapy, and event rates, AHF clinical trial enrollment has transitioned from North America and Western Europe to Eastern Europe, South America, and Asia-Pacific where regulatory burden and cost of conducting research may be less prohibitive. It is unclear if the results of clinical trials conducted outside of North America are generalizable to US patient populations.

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Article Synopsis
  • 12-lead ECG is essential for assessing cardiac ischemia, but traditional equipment limits its use; smartphones could provide a more accessible alternative for ECG testing.
  • A preliminary study with 6 patients compared traditional 12-lead ECGs to smartphone ECGs, using the AliveCor™ Heart Monitor, showing strong correlation in results.
  • The smartphone ECG demonstrated good diagnostic capabilities for acute ischemia, indicating the need for further research to establish its accuracy and practical applications.
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Background: Studies have individually reported the relationship of age, cardiac risk factors, and history of preexisting coronary artery disease (CAD) for predicting acute coronary syndromes in chest pain patients undergoing cardiac stress testing. In this study, we investigate the interplay of all these factors on the incidence of acute coronary syndromes to develop a tool that may assist physicians in the selection of appropriate chest pain patients for stress testing.

Methods: Retrospective analysis of a prospectively acquired database of consecutive chest pain patients undergoing nuclear stress testing.

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Background: Since 1991, the incidence of injuries associated with pneumatic and explosive powered nail guns has steadily been rising due to increasing use of these devices by the untrained consumer. The vast majority of injuries involve the extremities, but injuries have been reported to occur in virtually every area of the body.

Objective: Discuss the epidemiology, pathophysiology, and management of penetrating cardiac nail gun injuries.

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Carbon monoxide (CO) poisoning remains a common cause of poisoning in the United States. We describe a case where responding fire department personnel encountered a sick employee with a headache at an automotive brake manufacturing plant. Using both atmospheric CO monitoring and pulse CO-oximetry technology, fire department personnel were able to diagnose the cause of the patient's illness and later identify the source of CO in the plant.

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Severe winter weather, such as ice storms, that results in loss of electrical power, is frequently mentioned as a contributing factor in acute carbon monoxide (CO) poisoning. However, in our literature review, such events are infrequently reported. This article reports on such an event in which more than 200 patients were evaluated and treated at a single facility because of the crippling effects of an ice storm leading to prolonged loss of power and subsequent catastrophes with alternative heating and cooking sources.

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Bombings and other blast-related events place severe demands on pre-hospital and in-hospital systems. The resulting surge of victims can overwhelm the resources of any facility not prepared for such an event. The September 11 terrorist attacks underscore the urgency of our need for preparedness.

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