Publications by authors named "Harry L Stannard"
Commun Biol
September 2022
Article Synopsis
- Influenza antivirals, especially in combination, are crucial for managing flu epidemics and potential pandemics, as they can help prevent drug resistance and enhance patient recovery.
- Two immunocompromised patients showed that a combination of antivirals could lead to the emergence of resistant influenza viruses, specifically with mutations NA-H275Y and PA-I38T.
- Although these resistant strains can transmit between hosts, their overall viral fitness is lower than that of the wild type (WT) virus, indicating that large-scale community transmission of these mutants is unlikely.
