Encapsulins, virus capsid-like bacterial nanocompartments have emerged as promising tools in medicine, imaging, and material sciences. Recent work has shown that these protein-bound icosahedral 'organelles' possess distinct properties that make them exceptionally usable for nanotechnology applications. A key factor contributing to their appeal is their ability to self-assemble, coupled with their capacity to encapsulate a wide range of cargos.
View Article and Find Full Text PDFIncreasing efficiency is an important driving force behind cellular organization and often achieved through compartmentalization. Long recognized as a core principle of eukaryotic cell organization, its widespread occurrence in prokaryotes has only recently come to light. Despite the early discovery of a few microcompartments, such as gas vesicles and carboxysomes, the vast majority of these structures in prokaryotes are less than 100 nm in diameter-too small for conventional light microscopy and electron microscopic thin sectioning.
View Article and Find Full Text PDF