Chemical composition is maintained in poorly conserved intrinsically disordered regions and suggests a means for their classification.

Intrinsically disordered regions in proteins are known to evolve rapidly while maintaining their function. However, given their lack of structure and sequence conservation, the means through which they stay functional is not clear. Poor sequence conservation also hampers the classification of these regions into functional groups.

CELLPEDIA: a repository for human cell information for cell studies and differentiation analyses.

CELLPEDIA is a repository database for current knowledge about human cells. It contains various types of information, such as cell morphologies, gene expression and literature references. The major role of CELLPEDIA is to provide a digital dictionary of human cells for the biomedical field, including support for the characterization of artificially generated cells in regenerative medicine.

Efficient determination of cluster boundaries for analysis of gene expression profile data using hierarchical clustering and wavelet transform.

The existing methods for clustering of gene expression profile data either require manual inspection and other biological knowledge or require some cut-off value which can not be directly calculated from the given data set. Thus, the problem of systematic and efficient determination of cluster boundaries of clusters in gene expression profile data still remains demanding. In this context, we have developed a procedure for automatic and systematic determination of the boundaries of clusters in the hierarchical clustering of gene expression data based on the ratio of with-in class variance and between-class variance, which can be fully calculated from the given expression data.