Publications by authors named "Harrish Nithianandan"

Purpose: This study aims to identify clinical similarities and differences between males and females presenting with orbital fracture.

Methods: Patient charts of adult orbital fracture cases diagnosed via computed tomography and referred by a level 1 trauma center to the McGill University Health Centre between August 2015 to January 2018 were examined and analyzed. Clinical parameters included age, sex, mechanism of injury, morphology of orbital fracture, symptoms and examination features, and rates of ocular pathology.

View Article and Find Full Text PDF
Article Synopsis
  • This case report details a 20-year-old woman who developed serious complications, including orbital compartment syndrome and peripheral neuropathy, following a vitrectomy surgery for retinal detachment.
  • The patient's symptoms included significant eye movement issues and facial abnormalities due to extensive gas accumulation in the orbit and surrounding areas, which were confirmed by a CT scan.
  • Urgent surgical intervention through lateral canthotomy and cantholysis was performed, leading to resolution of most symptoms, and the patient achieved improved vision by week 7 post-surgery.
View Article and Find Full Text PDF

Objective: Subconjunctival hemorrhage (SCH) is a common presentation in patients with orbital trauma and often warrants investigation of underlying ocular pathology. Our study aims to assess the significance of SCH severity, graded in a spatial 0-360° manner, as a predictor for ocular pathology in patients with orbital fracture.

Design: Retrospective chart review.

View Article and Find Full Text PDF

Aim: To determine the refractive accuracy of the Haigis, Barrett Universal II (Barrett), and Hill-radial basis function 2.0 (Hill-RBF) intraocular lens (IOL) power calculations formulas in eyes undergoing manual cataract surgery (MCS) and refractive femtosecond laser-assisted cataract surgery (ReLACS).

Methods: This was a REB-approved, retrospective interventional comparative case series of 158 eyes of 158 patients who had preoperative biometry completed using the IOL Master 700 and underwent implantation of a Tecnis IOL following uncomplicated cataract surgery using either MCS or ReLACS.

View Article and Find Full Text PDF

The most common ophthalmic manifestation of sickle cell disease (SCD) is sickle cell retinopathy (SCR), which can lead to loss of vision due to complications of proliferative sickle retinopathy (PSR). Eventually, vitreoretinal surgery may be indicated in these patients to help preserve or improve vision. Unfortunately, SCD can cause systemic and ophthalmic vaso-occlusive and ischemic complications, which necessitates adequate perioperative planning in these patients undergoing surgery.

View Article and Find Full Text PDF

Purpose: This systematic review examined the relationship between industry funding and the presence of spin in high-impact studies evaluating intravitreal corticosteroid therapy for diabetic macular edema.

Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. MEDLINE and Embase were systematically searched from inception through July 16, 2018, for randomized controlled trials and meta-analyses investigating the treatment of patients with diabetic macular edema using intravitreal corticosteroid therapy.

View Article and Find Full Text PDF

Purpose: To assess the 1-year surgical outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in young to middle-aged patients.

Design: Retrospective case series.

Participants: Eyes of patients between 18 and 64 years of age who underwent GATT, with and without concomitant cataract surgery, at 2 academic centers in Montreal, Canada.

View Article and Find Full Text PDF

Purpose: To evaluate the value of biomarkers to prognosticate outcomes in patients with pulmonary embolism among studies of sound methodical quality.

Methods: Ovid MEDLINE, Embase, CENTRAL, and non-indexed citations were searched from inception to March 2019. Biomarkers of interest included troponin I (TnI), troponin T (TnT), high-sensitive TnT (HS-TnT), brain natriuretic peptide (BNP), N-terminal pro-BNP (NT-proBNP), heart fatty acid binding protein (H-FABP), and D-dimer (DD).

View Article and Find Full Text PDF

Objective: To estimate the hospital costs of managing anterior epistaxis in the Emergency Department at a Tertiary Care centre in Canada.

Material And Methods: A cost analysis was conducted based on a retrospective review of Emergency Department visits from January 2012 to May 2014. A consecutive sample of adult patients with a diagnosis of anterior epistaxis was included.

View Article and Find Full Text PDF

Purpose: To investigate the anatomical success rate associated with rhegmatogenous retinal detachment (RRD) repair without postoperative head positioning.

Methods: Data on 182 individuals undergoing pars plana vitrectomy (PPV) with or without phacoemulsification or scleral buckle for primary RRD with intraocular tamponade were retrospectively reviewed. The primary outcome was the initial anatomical success rate.

View Article and Find Full Text PDF

Objective: Social participation benefits health. We assessed the relationship between self-reported visual impairment (VI) and glaucoma versus seniors' social participation.

Methods: Data from individuals aged ≥65 years responding to the Canadian Community Health Survey Healthy Aging 2008/2009 (n = 16,369) was analyzed.

View Article and Find Full Text PDF

Purpose: To report on outcomes of the efficacy and safety in 1 of the largest series of eyes undergoing either conventional manual cataract surgery (MCS) or refractive femtosecond laser-assisted cataract surgery (ReLACS).

Design: Retrospective, consecutive, interventional comparative case series.

Methods: This study included 3144 consecutive eyes, of which 1580 were treated via MCS, and 1564 were treated via ReLACS at Uptown Surgical Centre in Vaughan, Ontario, Canada.

View Article and Find Full Text PDF

Patients with advanced-stage pancreatic cancer are typically burdened by many symptoms that impair functioning and worsen quality of life. We report an exceptional case of a 73-year-old woman with T4N1M0 adenocarcinoma of the uncinate process of the pancreas who developed significant gastric outlet obstruction - an uncommon yet potentially life-threatening complication of disease progression. She developed progressive abdominal pain and emesis, and profound dilatation of her stomach was detected on a radiation therapy simulation CT scan that required urgent decompression.

View Article and Find Full Text PDF