Publications by authors named "Harris J J M D Song"
Article Synopsis
- The effectiveness of adjuvant radioiodine (RAI) therapy after reoperation for persistent or recurrent differentiated thyroid cancer (DTC) is debated, with concerns about potential side effects.
- A systematic review included six studies with 437 patients and found no significant benefits of RAI in terms of progression-free or overall survival, nor in treatment response or recurrence rates.
- The authors emphasize the need for higher-quality randomized trials to better assess RAI's effectiveness and recommend using RAI selectively for high-risk patients only.
Importance: Hearing loss is associated with cognitive decline. However, it is unclear if hearing restorative devices may have a beneficial effect on cognition.
Objective: To evaluate the associations of hearing aids and cochlear implants with cognitive decline and dementia.
Objectives: Anti-PD1 antibody has emerged as a promising immunotherapeutic option in patients with recurrent and/or metastatic nasopharyngeal cancers (RM-NPC). We aim to summarise existing evidence on the use of anti-PD1 antibodies in the treatment of these patients and compare its effectiveness with standard-of-care palliative chemotherapy. Our secondary aim is to explore potential combination therapies with anti-PD1 antibodies.
View Article and Find Full Text PDFBackground: Glaucoma and chronic kidney disease (CKD) are prevalent and debilitating conditions, with common pathogenic pathways like oxidative stress and fluid dysregulation. We evaluated if there is a bidirectional association between them, as previous studies have yielded conflicting results.
Methods: In this systematic review and meta-analysis, we searched PubMed, Embase and Cochrane Library from inception until 15 June 2021, including full-length English articles published in peer-reviewed journals reporting on glaucoma and CKD as either exposure or outcome, among participants aged ≥18 years.
Importance: Olfactory impairment is highly prevalent and associated with multiple comorbidities, including neurodegenerative, cardiovascular, nutritional, and immune disorders. However, epidemiologic associations between olfactory impairment and mortality are discordant.
Objective: To systematically clarify the epidemiologic associations between olfactory impairment and mortality.
Associations of Hearing Loss and Dual Sensory Loss With Mortality: A Systematic Review, Meta-analysis, and Meta-regression of 26 Observational Studies With 1 213 756 Participants.
JAMA Otolaryngol Head Neck Surg
March 2022
Importance: Hearing loss (HL) and dual sensory loss (DSL) are prevalent, disabling, and associated with numerous age-related health conditions, including dementia and frailty. To date, no evidence-based summary of their mortality risk is available.
Objective: To clarify the epidemiological associations between HL/DSL and mortality.
Surgical traineeship is essential but must be safe for patients. In thyroid surgery, surgeon volume correlates with improved clinical/economic outcomes. However, it is presently unclear how far does trainee participation affect post-thyroidectomy complication rates in real-world and randomized data.
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