Contraceptive implants: providing better choice to meet growing family planning demand.

Contraceptive implants are extremely effective, long acting, and suitable for nearly all women-to delay, space, or limit pregnancies-and they are increasingly popular. Now, markedly reduced prices and innovative service delivery models using dedicated non-physician service providers offer a historic opportunity to help satisfy women's growing need for family planning.

Pharmacokinetics of oxaliplatin (NSC 266046) alone and in combination with paclitaxel in cancer patients.

Unlabelled: Oxaliplatin (OPT), a third-generation platinating agent, is currently being evaluated in a phase II clinical trial in head and neck cancer patients and in a phase I clinical trial in combination with paclitaxel (TXL).

Purpose: The aim of this study was to investigate the pharmacokinetics and biological correlates of OPT alone as well as the potential pharmacokinetic interaction between OPT and TXL.

Methods: In the phase II study, OPT was given alone as a 2-h i.