Fluorophotometric and tonometric evaluation of ocular effects following aqueocentesis performed with needles of various sizes in dogs.

Objective: To measure ocular effects (blood-aqueous barrier breakdown and intraocular pressure [IOP]) following aqueocentesis performed with needles of various sizes in dogs.

Animals: 28 healthy adult dogs.

Procedures: 24 dogs underwent unilateral aqueocentesis (24 treated eyes and 24 contra-lateral untreated eyes); 25-, 27-, or 30-gauge needles were used in 3 treatment groups (n = 8/group).

Surgical correction of periocular fat pads and entropion in a potbellied pig (Sus scrofa).

A 16-year-old Vietnamese potbellied pig was examined because of recurrent ocular discharge and reduced visual ability. Bilateral upper eyelid entropion and impaired vision secondary to periocular fat deposition were diagnosed. Surgical correction with excision of subdermal fat and redundant skin was performed to address both issues.

NC-1059: a channel-forming peptide that modulates drug delivery across in vitro corneal epithelium.

Purpose: The goal of this study was to determine whether a synthetic peptide, NC-1059, can modulate the corneal epithelium to increase the permeation of therapeutic agents across this barrier.

Methods: An in vitro system employing transformed human corneal epithelial (THCE) cells was optimized for this study. Culture conditions were identified to promote formation of a confluent monolayer that rapidly develops a substantial transepithelial electrical resistance.

Modified lateral orbitotomy for vision-sparing excision of a zygomatic mucocele in a dog.

A 1-year-old Shar Pei presented for recent-onset exophthalmos and right peri-ocular facial swelling. Physical examination revealed the facial mass was of soft-tissue consistency and nonpainful to the dog. Due to inability to retropulse the globe during ophthalmologic examination, it was suspected the mass had impinged into the orbit, resulting in rostral displacement of the globe.

The effects of bimatoprost and unoprostone isopropyl on the intraocular pressure of normal cats.

Objective: To evaluate the effects on intraocular pressure (IOP), pupillary diameter (PD), blepharospasm score, conjunctival injection score, and aqueous humor flare score when either 0.03% bimatoprost solution is applied once daily or 0.15% unoprostone isopropyl solution is applied twice daily topically to the eyes of normal cats.

Residency selection perceptions held by diplomates of the American College of Veterinary Ophthalmologists and veterinary ophthalmology residency applicant data.

Diplomates from the American College of Veterinary Ophthalmologists (DACVOs) who do not select residents concur with DACVOs involved in the selection of residents that it is a subjective process. Both groups believe that residents are selected on the basis of their perceived intelligence, hardworking attitude, and effective communication skills, along with the impression that the resident will fit well into a particular work environment. Survey data from successful veterinary ophthalmology resident applicants identify several helpful criteria.

The tear film and ocular mucins.

Abstract The trilaminar tear film, composed of the lipid, aqueous and mucin layers, has many functions including defending the ocular surface. The aqueous layer has several soluble antimicrobial factors that protect the ocular surface. Ocular mucins have recently been studied with regard to their role in the defense of the eye as well as in dry eye syndromes.

Effects of atracurium on intraocular pressure, eye position, and blood pressure in eucapnic and hypocapnic isoflurane-anesthetized dogs.

Objective: To determine effects of atracurium on intraocular pressure (IOP), eye position, and arterial blood pressure in eucapnic and hypocapnic dogs anesthetized with isoflurane.

Animals: 16 dogs.

Procedure: Ventilation during anesthesia was controlled to maintain Paco2 at 38 to 44 mm Hg in group- I dogs (n = 8) and 26 to 32 mm Hg in group-II dogs (8).

Methods and characteristics used in resident selection within the American College of Veterinary Ophthalmologists.

A survey of Diplomates from the American College of Veterinary Ophthalmologists, which trains residents, confirms that subjective criteria are most commonly used in selecting new residents. The ophthalmologist(s) who oversee(s) the training was/were primarily responsible for resident selection. In general, Diplomates seemed to be searching for a resident who was intelligent, could communicate well, was hard working, and had good interpersonal skills.

A field trial of autogenous Moraxella bovis bacterin administered through either subcutaneous or subconjunctival injection on the development of keratoconjunctivitis in a beef herd.

The primary purpose of these experiments was to evaluate an autogenous Moraxella bovis bacterin administered through 2 separate routes of inoculation. An autogenous bacterin was manufactured by using M. bovis recovered from the herd.

Normal conjunctival flora in the North American opossum (Didelphis virginiana) and raccoon (Procyon lotor).

We documented the normal conjunctival bacterial flora from 17 opossums (Didelphis virginiana) and 10 raccoons (Procyon lotor) trapped in Manhattan, Kansas (USA) from November 1999 to January 2000. Both raccoons and opossums were free of apparent ocular disease. The inferior conjunctival sacs of each animal were swabbed for aerobic bacterial and Mycoplasma culture and polymerase chain reaction (PCR) for Mycoplasma and Chlamydia detection.

Evaluation of lysozyme and lactoferrin in lacrimal and other ocular glands of bison and cattle and in tears of bison.

Objective: To evaluate lactoferrin and lysozyme content in various ocular glands of bison and cattle and in tears of bison.

Sample Population: Tissues of ocular glands obtained from 15 bison and 15 cattle and tears collected from 38 bison.

Procedure: Immunohistochemical analysis was used to detect lysozyme and lactoferrin in formalin-fixed, paraffin-embedded sections of the ocular glands.

Mimecan/osteoglycin-deficient mice have collagen fibril abnormalities.

Purpose: To study the role of mimecan, a member of the small leucine-rich proteoglycans (SLRPs) gene family and one of the major components of the cornea and other connective tissues, mice that lack a functional mimecan gene were generated and characterized.

Methods: Mimecan-deficient mice were generated by gene-targeting using standard techniques. Mice were genotyped by Southern blot analysis.

Effect of topical ophthalmic latanoprost on intraocular pressure in normal horses.

The ocular effects of latanoprost ophthalmic solution were evaluated in two studies, with eight horses in each study. One eye of each horse was treated with latanoprost ophthalmic solution once daily for 5 days, and the opposite eye received a control solution of sterile eyewash. Intraocular pressure and pupillary diameter were measured daily for 5 days after treatment.