Publications by authors named "Harrar K"

Over the last few decades, field-effect transistor (FET)-based biosensors have demonstrated great potential across various industries, including medical, food, agriculture, environmental, and military sectors. These biosensors leverage the electrical properties of transistors to detect a wide range of biomolecules, such as proteins, DNA, and antibodies. This article presents a comprehensive review of advancements in the architectures of FET-based biosensors aiming to enhance device performance in terms of sensitivity, detection time, and selectivity.

View Article and Find Full Text PDF

This paper presents a novel framework for breast cancer detection using mammogram images. The proposed solution aims to output an explainable classification from a mammogram image. The classification approach uses a Case-Based Reasoning system (CBR).

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates factors predicting the risk of Total Knee Arthroplasty (TKA) in patients with knee osteoarthritis (KOA), given the absence of effective disease-modifying drugs.
  • The researchers analyzed 4,382 X-ray images and combined trabecular bone texture analysis with clinical and radiological data to create a new risk prediction model.
  • The new model achieved high accuracy (AUC of 0.92) compared to the traditional Kellgren-Lawrence model (AUC of 0.86), showing a significant improvement in identifying patients at risk for TKA.
View Article and Find Full Text PDF

Objectives: To examine whether trabecular bone texture (TBT) parameters assessed on computed radiographs could predict knee osteoarthritis (OA) progression.

Methods: This study was performed using data from the Osteoarthritis Initiative (OAI). 1647 knees in 1124 patients had bilateral fixed flexion radiographs acquired 48 months apart.

View Article and Find Full Text PDF

Food resources contaminated with spoilage or pathogenic microorganisms pose severe problems to all higher organisms. Here, we describe a food-hygienic strategy of the emerald cockroach wasp Ampulex compressa. The wasp larvae develop on and inside the American cockroach Periplaneta americana, a host that can harbor various putrefactive microbes, as well as human and insect pathogens.

View Article and Find Full Text PDF

The first enantioselective synthesis of (-)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.

View Article and Find Full Text PDF