Publications by authors named "Haroldo Gurgel Mota-Filho"

This study aimed to verify the efficacy of low-level laser irradiation (LLLI) on the proliferation of MC3T3-E1 preosteoblasts cultured on poly(lactic acid) (PLA) films. The produced films were characterized by contact angle tests, scanning electron microscopy (SEM), atomic force microscopy, differential scanning calorimetry, and X-ray diffraction. The MC3T3-E1 cells were cultured as three different groups: Control-cultured on polystyrene plastic surfaces; PLA-cultured on PLA films; and PLA + Laser-cultured on PLA films and submitted to laser irradiation (660 nm; 30 mW; 4 J/cm ).

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Article Synopsis
  • Low-level laser irradiation (LLLI) has a positive impact on the proliferation of dental pulp stem cells (DPSCs), with this study aiming to determine the effective energy density for promoting cell growth and viability.
  • Human DPSCs from healthy teeth were exposed to two energy densities (0.5 and 1.0 J/cm²), and those treated with 1.0 J/cm² showed significantly increased proliferation compared to the control group after certain time intervals.
  • The findings suggest that LLLI at 1.0 J/cm² can enhance DPSC growth while maintaining cell viability, positioning it as a valuable technique for future applications in tissue engineering and regenerative medicine.
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