Publications by authors named "Harold Zhu"
Article Synopsis
- A stroke can lead to aphasia, a language impairment, affecting many survivors, with some recovering in the first 6 months while others face lasting challenges.
- Research shows that the organization of brain networks may play a role in the severity of aphasia and recovery outcomes.
- A study of stroke survivors undergoing therapy revealed that pre-treatment brain network structure could predict their improvement in language abilities, indicating that network organization is crucial for recovery.
Brain imaging and genomics are critical tools enabling characterization of the genetic basis of brain disorders. However, imaging large cohorts is expensive and may be unavailable for legacy datasets used for genome-wide association studies (GWASs). Using an integrated feature selection/aggregation model, we developed an image-mediated association study (IMAS), which utilizes borrowed imaging/genomics data to conduct association mapping in legacy GWAS cohorts.
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