Publications by authors named "Harold V Cohen"

When providing dental treatment, the dental clinician (DC) is expected to be knowledgeable in recognition and emergency management of an allergic response. Common manifestations of localized allergic responses can present as a rash or hives (urticaria), running of the nose, and swelling of the lips, eyes, face, respiratory and gastrointestinal mucosa. More critically, there is the potential for breathing difficulties from laryngeal swelling.

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As healthcare professionals, we deal daily with "aging"'factors relating to our patients' dental treatment planning (and to ourselves). We are all are expressions of our DNA-the long molecules in our cells' nuclei that contain our genes which determine how proteins will be made to express who we are. Although genetics can be a confusing subject to understand, when trying to understand DNA, perhaps consider that you Do Not Abandon learning some of the basics of genetics.

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This overview is intended as a baseline understanding of viral biology, pathology and developing medical therapeutic regimens using viral vectors. The dental clinician is encouraged to pursue further information as patients present with viral related illness or are undergoing emerging therapies.

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A critical and recurrent situation faced by the dental clinician (DC) is that of providing care to patients who may be at risk for excessive bleeding during care or post-operatively. Bleeding disorders may be due to congenital and/or acquired conditions affecting platelets and/or the coagulation process. Less often, the DC may be providing care to a patient who has an excessive clotting disorder.

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A recent occurrence in dental practice is the noting of new "blood thinners" when the clinician is reviewing a patient's medical history and medications. "Doc, I take Pradaxa or Effient or Xarelto" etc. After many years of the widespread use of aspirin and Coumadin there has appeared a new generation of medications focused on reducing thromboembolic events in patients at risk.

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Cardiovascular medicine treatments now include an increasing number of cardiac valve replacements; approximately 60,000 patients may undergo heart valve replacement per year. Dentists will be seeing an increasing number of patients who have undergone this surgical intervention. This paper will overview the types of valve replacements and suggested patient management in the dental setting.

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Objective: The objective of this study was to present a comprehensive model for the pathogenesis of bisphosphonate-associated osteonecrosis of the jaw (BON).

Study Design: Review of PubMed literature relevant to BON, bisphosphonates (BPs), and bone remodeling.

Results: Six case reports of spontaneous resolution of BON lesions following administration of teriparatide (Forteo; Eli Lilly and Co.

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An emerging problem for patients taking bisphosphonate (BSP) medications for osteoporosis or cancer therapies has been the occurrence of osteonecrosis of the jaws (ONJ), most often after dental surgical procedures. ONJ can be a persistent and discomforting condition that can also be refractory to various therapies. This article will overview the pathophysiology of ONJ, the proposed causal relationship between BSP use and ONJ, and the current guidelines for dental care of a patient who will be, or is taking, this class of medications.

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There have been many papers reviewing the dental office assessment and management of the patient with a seizure disorder. This paper will discuss two updated medical management issues which may impact dental office care of the seizure patient. The focus will on the use of a pacemaker-like device connected to the vagus nerve as part of seizure control.

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There have been many papers reviewing the dental office assessment and management of the patient with a seizure disorder. This paper will discuss two updated medical management issues which may impact dental office care of the seizure patient. The focus will on the use of a pacemaker-like device connected to the vagus nerve as part of seizure control.

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Patients who have experienced significant brain injury (such as hemorrhagic stroke or trauma) can suffer brain damage that leads to altered neurologic functioning. One such ill effect is the development of aberrant mandibular reflexes that may inflict serious trauma to oral and labial tissues. As primary oral health care providers, dental clinicians may be called upon to function as part of the medical team managing the patient.

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Medical management of the head and neck cancer patient (HNCP) most often will include radiation therapy to the head and neck region. HNCPs with malignant disease require judicious dental treatment planning prior to radiation therapy (RT) and/or chemotherapy. RT can result in a multitude of adverse effects, both reversible and irreversible.

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In today's complex healthcare environment, there is an increasing incidence of patients with serious medical issues who may present for dental care. Excessive post-operative bleeding is always a concern of the dentist. It is essential that the contemporary oral healthcare provider be familiar with: 1.

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With today's medically complex population of ambulatory patients, it is essential that the dental clinician possess a working knowledge of those medical issues that may impact a practice. This is most critical in those patients who present with a bleeding risk. Acquiring a thorough history with necessary medical information and possessing a basic knowledge of bleeding disorders will guide the clinician in deciding whether to treat or to make an appropriate referral.

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