The Prediction of Tumorigenesis Onset Using Parameters from Chaotic Attractor Models.

Tumorigenesis can be modeled as a system of chaotic, nonlinear differential equations. From the analysis of these equations in state space, the onset of tumorigenesis can be predicted based on the status of parameters from the model.

The Development of Antisense RNA Treatments Using Engineered Protein Substrates.

Current efforts to design supercharged protein assemblies have opened the door for the creation of substrates that could be used for drug delivery and as substrates for antiviral delivery mechanisms. We explore the potential for antiviral delivery with antisense RNAs that bind their phosphate backbone to the charge of an engineered protein oligomer, providing structural integrity to the RNA strand and adding possible steric effects to prevent reaction with unintended targets.

The Effects of Quantum Entanglement on Chromatin and Gene Expression.

Quantum entanglement has recently been demonstrated in macroscopic structures at the scale of microns. The densely packed chromatin that efficiently stores DNA strands may allow for gene expression through epigenetic modifiers within the close proximity of nearby strands and may also experience gene expression through quantum entanglement of epigenetic modifiers. Such an approach may have an evolutionary advantage in the densely packed realm of chromatin.

Challenges and Successes of an Audio-Technician Training Program in Guatemala.

Hearing healthcare outreach in developing countries is ill defined and inundated with sustainability challenges. One method to facilitate sustainable efforts is by training local personnel on certain aspects of hearing healthcare. The purpose of this descriptive study was to identify the challenges and successes of an audio-technician training program conducted in various regions throughout Guatemala.

The burgeoning role of global health diplomacy to alleviate suffering of cancer patients in low- and middle-income countries.

The science of global health diplomacy (GHD) consists of cross-disciplinary, multistakeholder credentials comprised of national security, public health, international affairs, management, law, economics and trade policy. GHD is well placed to bring about better and improved multilateral stakeholder leverage and outcomes in the prevention and control of cancer. It is important to create an evidence base that provides clear and specific guidance for health practitioners in low- and middle-income countries (LMICs) through involvement of all stakeholders.

BPEI-Induced Delocalization of PBP4 Potentiates β-Lactams against MRSA.

With its high morbidity rate and increasing resistance to treatment, methicillin-resistant (MRSA) is a grave concern in the medical field. In methicillin-susceptible strains, β-lactam antibiotics disable the penicillin binding proteins (PBPs) that cross-link the bacterial cell wall. However, methicillin-resistant strains have PBP2a and PBP4, which continue enzymatic activity in the presence of β-lactam antibiotics.

On Defining Irritability and its Relationship to Affective Traits and Social Interpretations.

Irritability has gained recognition as a clinically significant trait in youth and adults that when persistent and severe, predicts poor outcomes throughout life. However, its definition, measurement, and relationship to similar constructs remain poorly understood. In a community sample of adults (N=458; 19-74 years; M=40.

Design of a Compensator Network to Stabilize Chaotic Tumor Growth.

Tumorigenesis can be modeled as a system of chaotic, nonlinear differential equations. From the analysis of these equations in state space, a feedback compensator is designed to stabilize the system based on a desired response. The feedback array constants represent four transducer molecules which could be used for any tumor type that obeys the same dynamics as the model, reducing drug investment requirements for a wider range of cancer treatment.

Development and preliminary effectiveness of an innovative treatment for binge eating in racially diverse adolescent girls.

Introduction: Binge and loss of control (LOC) eating are significant concerns among many adolescents and are associated with poor physical, social, and psychological functioning. Black girls appear to be particularly vulnerable to binge and LOC eating. Yet, empirically validated, culturally sensitive treatments for these disordered eating behaviors are not well established.

Naturalizing phenomenology - A philosophical imperative.

Phenomenology since Husserl has always had a problematic relationship with empirical science. In its early articulations, there was Husserl's rejection of 'the scientific attitude', Merleau-Ponty's distancing of the scientifically-objectified self, and Heidegger's critique of modern science. These suggest an antipathy to science and to its methods of explaining the natural world.

The initial management of epistaxis.

Epistaxis affects up to 60% of people. The basic first aid management of epistaxis is clearly stated in the literature and guidelines. Anecdotal evidence would suggest that these principles are not understood by patients and are not being conveyed to patients by their doctors.

Chaotic attractors in tumor growth and decay: a differential equation model.

Tumorigenesis can be modeled as a system of chaotic nonlinear differential equations. A simulation of the system is realized by converting the differential equations to difference equations. The results of the simulation show that an increase in glucose in the presence of low oxygen levels decreases tumor growth.

Negative affective experiences in relation to stages of eating disorder recovery.

The purpose of this study was to examine a collection of negative affect symptoms in relation to stages of eating disorder recovery. Depressive symptoms, anxiety symptoms, loneliness, and perceived stress are known to be present in individuals with eating disorders; however, less is known about the presence of such constructs throughout the recovery process. Does this negative affect fog continue to linger in individuals who have recovered from an eating disorder? Female participants seen at some point for an eating disorder at a primary care clinic were categorized into one of three groups using a stringent definition of eating disorder recovery based on physical, behavioral, and psychological criteria: active eating disorder (n=53), partially recovered (n=15; psychological criteria not met), and fully recovered (n=20; all recovery criteria met).

Biology and rearing of Cleruchoides noackae (Hymenoptera: Mymaridae), an egg parasitoid for the biological control of Thaumastocoris peregrinus (Hemiptera: Thaumastocoridae).

Cleruchoides noackae Lin and Huber (Hymenoptera: Mymaridae) is a solitary egg parasitoid of Thaumastocoris peregrinus Carpintero and Dellapé (Hemiptera: Thaumastocoridae). The parasitoid was first described in 2009 and its biology and rearing are poorly understood. A key obstacle to the use of C.

Evaluating the roles of anxiety and dimensions of perfectionism in dieting and binge eating using weekly diary methodology.

This study examined the relations between weekly reports of anxiety, dimensions of trait perfectionism, and dieting and binge eating over the course of 11 weeks. Participants were 406 college women who completed a battery of questionnaires at Time 1 that assessed trait-like characteristics (e.g.

Examining social physique anxiety and disordered eating in college women. The roles of social comparison and body surveillance.

Social physique anxiety has been found to be associated with disordered eating. However, what is not yet known is what behaviors college women may engage in that strengthen this relation. In the current study, we examined two possible moderating factors, social comparison and body surveillance.

Development and validation of the Body, Eating, and Exercise Comparison Orientation Measure (BEECOM) among college women.

We constructed and validated a measure of comparison dimensions associated with eating pathology, namely, the body, eating, and exercise comparison orientation measure (BEECOM). Participants were 441 undergraduate women. In Study 1, items were generated and refined via exploratory factor analysis, yielding three interpretable factors (i.

The inter-relationships between vegetarianism and eating disorders among females.

When individuals with a suspected or diagnosed eating disorder adopt a vegetarian diet, health care professionals might worry that this choice could function as a socially acceptable way to legitimize food avoidance. Yet only limited research has examined vegetarianism in relation to eating disorders. Our study objectives were to compare individuals with and without an eating disorder history and individuals at different stages of eating disorder recovery on past and current vegetarianism and motivations for and age at becoming vegetarian.

What if high expectations feel good? Perceived parental expectations, their meanings, and bulimic symptoms in Black and White college women.

This study aimed to test an interactive model of perceived parental expectations and the meaning of those expectations in relation to bulimic symptoms in Black (n=97) and White (n=179) college women. Black young women reported higher parental expectations and attached more positive meanings to high parental expectations, in comparison to their White peers. There was an interactive effect for Black young women such that, in the context of perceived high parental expectations, interpreting high parental expectations as negative was associated with higher levels of bulimic symptoms whereas interpreting high expectations as positive was associated with lower levels of bulimic symptoms.

The quality of information on three common ENT procedures on the Internet.

Background: The Internet hosts a large number of high-quality medical resources and poses seemingly endless opportunities to inform, teach, and connect professionals and patients alike. However, it is difficult for the lay person to distinguish accurate from inaccurate information.

Aim: This study was undertaken in an attempt to assess the quality of information on otolaryngology available on the Internet.

Explaining the relation between thin ideal internalization and body dissatisfaction among college women: the roles of social comparison and body surveillance.

Sociocultural models of disordered eating lack comprehensive explanations as to how thin ideal internalization leads to body dissatisfaction. This study examined two social psychological theories as explanations of this relation, namely social comparison and objectification theories, in a sample of 265 women attending a Southeastern university. Social comparison (both general and appearance-related) and body surveillance (the indicator of objectification) were tested as mediators of the relation between thin ideal internalization and body dissatisfaction using bootstrapping analyses.

Perceptions of parental attitudes toward body and eating: associations with body image among Black and White college women.

This study examined Black and White young women's perceptions of parental body- and eating-related attitudes and behaviors from growing up and the relations of these parental factors with their current body image. Female undergraduates (97 Black women, 179 White women) completed questionnaires of perceptions of parental attitudes/behaviors related to body image and eating and of their current body image, operationalized as weight/shape concern. Results indicated that perceived parental communication was more strongly related to body image than perceived parental modeling in both ethnic groups, and that there were some differences in how frequently Black and White women reported encountering specific maternal messages about the body or eating.