Impact factors and publication times of original scientific research in radiology journals.

Purpose: The time from article submission to publication in peer-reviewed scientific journals is variable and can be prolonged, which slows the dissemination of research and can influence the academic progress of authors. This study evaluated the publication times for articles in radiology journals, in particular the relationship between turnaround times and journal impact factors (IFs).

Methods: Bibliometric data was obtained from Journal Citation Reports to conduct a comparative analysis of radiology journals against those in other disciplines of clinical medicine using highest IF, median IF, cited half-life, immediacy index, and number of journals.

ReMIND: The Brain Resection Multimodal Imaging Database.

The standard of care for brain tumors is maximal safe surgical resection. Neuronavigation augments the surgeon's ability to achieve this but loses validity as surgery progresses due to brain shift. Moreover, gliomas are often indistinguishable from surrounding healthy brain tissue.

IGFBP-1 in Cardiometabolic Pathophysiology-Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice.

We have previously reported that overexpression of human insulin-like growth factor binding protein (IGFBP)-1 in mice leads to vascular insulin sensitization, increased nitric oxide bioavailability, reduced atherosclerosis, and enhanced vascular repair, and in the setting of obesity improves glucose tolerance. Human studies suggest that low levels of IGFBP-1 are permissive for the development of diabetes and cardiovascular disease. Here we seek to determine whether loss of IGFBP-1 plays a causal role in the predisposition to cardiometabolic disease.

Insulin-like growth factor binding proteins and angiogenesis: from cancer to cardiovascular disease.

Angiogenesis is a tightly regulated activity that is vital during embryonic development and for normal physiological repair processes and reproduction in healthy adults. Pathological angiogenesis is a driving force behind a variety of diseases including cancer and retinopathies, and inhibition of angiogenesis is a therapeutic option that has been the subject of much research, with several inhibitory agents now available for medical therapy. Conversely, therapeutic angiogenesis has been mooted as having significant potential in the treatment of ischemic conditions such as angina pectoris and peripheral arterial disease, but so far there has been less translation from lab to bedside.