Publications by authors named "Harmonie Durand"
The implementation of MALDI-TOF MS in medical microbiology laboratories has revolutionized practices and significantly reduced turnaround times of identification processes. However, although bacteriology quickly benefited from the contributions of this technique, adjustments were necessary to accommodate the specific characteristics of fungi. MALDI-TOF MS is now an indispensable tool in clinical mycology laboratories, both for the identification of yeasts and filamentous fungi, and other innovative uses are gradually emerging.
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- Glioblastoma is a highly aggressive brain cancer, and accurate tumor grading is crucial for effective treatment, but current methods are limited in unbiased classification.
- Researchers applied a fast MALDI-TOF MS protocol, originally for classifying microorganisms, to glioma cell lines to improve tumor detection.
- The study found that MALDI-TOF could effectively differentiate between various glioblastoma cell types, suggesting it could enhance tumor classification and lead to better, personalized treatment options.
This study describes an innovative strategy for rapid detection and identification of bacteria causing endophthalmitis, combining the use of an automated blood culture system with MALDI-TOF mass spectrometry methodology. Using this protocol, we could identify 96% of 45 bacterial strains isolated from vitreous samples collected in acute post-operative endophthalmitis patients.
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