Publications by authors named "Harley D"

Background: The Transformative Care Continuum (TCC) emerged in 2018 at Ohio University's Heritage College of Osteopathic Medicine, combining a three-year medical education track with a three-year family medicine residency. TCC aligns evolving family physician roles through the Kern model, AMA's Master Adaptive Learner model, Health Systems Science Training, and Kirkpatrick's evaluation model.

Methods: The TCC curriculum emphasizes intensive coaching, clinical encounter video evaluation, reflection, and case-log review.

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  • Enterobacterales bloodstream infections (E-BSI) pose a significant health threat to children in Queensland, Australia, with a notable rise in infection rates observed from 2000 to 2019.
  • A total of 1980 E-BSI cases were recorded, leading to an increase in the standardized incidence rate from 7.3 to 12.9 cases per 100,000 child years, with E. coli and Salmonella sp. being the most common pathogens.
  • The study highlights the growing antimicrobial resistance, particularly in E. coli, and emphasizes the need for including children in clinical trials for more effective treatment options.
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Quantum hardware has the potential to efficiently solve computationally difficult problems in physics and chemistry to reap enormous practical rewards. Analogue quantum simulation accomplishes this by using the dynamics of a controlled many-body system to mimic those of another system; such a method is feasible on near-term devices. We show that previous theoretical approaches to analogue quantum simulation suffer from fundamental barriers which prohibit scalable experimental implementation.

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Children's early awareness about cancer, through exposure to cancer biology and prevention strategies and research principles, is a promising focus of education and learning. It may also benefit the pipeline of people entering into science, technology, engineering, and math (STEM) careers. We describe an educational pilot program for elementary school students, using developmentally appropriate activities focused on cancer at a museum dedicated to children's maker-centered learning and STEM.

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Objective: The burden of extra-pulmonary tuberculosis (EPTB) is not well quantified in TB endemic countries such as those in sub-Saharan Africa. This study aimed to quantify that burden via a systematic review of the prevalence of EPTB in African countries.

Methods: Studies were retrieved by searching five databases; 105 studies published between 1990 and 2023 were included.

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Ross River virus (RRV) is the most common mosquito-borne disease in Australia, with Queensland recording high incidence rates (with an annual average incidence rate of 0.05% over the last 20 years). Accurate prediction of RRV incidence is critical for disease management and control.

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The Leadbeater's possum () is a critically endangered nocturnal marsupial with a restricted range in the Central Highlands of Victoria, Australia. There are two genetically distinct populations divided by location: highland and lowland. Lowland possums exist in one remnant swamp forest and entered captivity in 2012 when ∼60 individuals remained.

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  • Adolescents with intellectual disability exhibit substantial health needs, as evidenced by a study on primary care encounters in southern Queensland, Australia.
  • The analysis showed that skin issues, along with psychological/behavioral and musculoskeletal problems, were the most common reasons for seeking primary care among these adolescents.
  • Prevalence rates revealed that autism spectrum disorder and asthma were the most prevalent conditions, while gastroesophageal reflux had the highest incidence, highlighting the necessity for tailored healthcare approaches and training for general practitioners.
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Identifying sex-linked markers in genomic datasets is important because their presence in supposedly neutral autosomal datasets can result in incorrect estimates of genetic diversity, population structure and parentage. However, detecting sex-linked loci can be challenging, and available scripts neglect some categories of sex-linked variation. Here, we present new R functions to (1) identify and separate sex-linked loci in ZW and XY sex determination systems and (2) infer the genetic sex of individuals based on these loci.

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Autistic adults experience stark health disparities and difficulties accessing health care. Their realities of managing complex health conditions are unknown. Our research explored the experience of Autistic adults self-managing diabetes.

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In Australia, there is a significant gap between health outcomes in Indigenous and non-Indigenous children, which may relate to inequity in health service provision, particularly in remote areas. The aim was to conduct a scoping review to identify publications in the academic and grey literature and describe 1) Existing health services for Indigenous children in remote Australia and service use, 2) Workforce challenges in remote settings, 3) Characteristics of an effective health service, and 4) Models of care and solutions. Electronic databases of medical/health literature were searched (Jan 1990 to May 2021).

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  • The study investigates the use of various psychotropic medications among adults with intellectual disabilities, finding that about 41% are prescribed these medications.
  • The analysis covered 24 studies, revealing specific medication usage rates: 31% for antipsychotics, 14% for antidepressants, and lower percentages for anxiolytics, hypnotics/sedatives, and psychostimulants.
  • The results highlighted significant variability between studies, indicating a need for further research to understand this variation and to assess the effectiveness and safety of medication prescriptions in this population.
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Objective: There is an expectation among the public and within the profession that the performance and outcome of neonatal intensive care units (NICUs) should be comparable between centres with a similar setting. This study aims to benchmark and audit performance variation in a regional Australian network of eight NICUs.

Design: Cohort study using prospectively collected data.

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Introduction: Increasing demand for integrated care necessitates interprofessional training of mental and behavioral professionals. This study examines the effect of an interprofessional training program for social work and counseling trainees (PRI-Care) in 3 areas: interprofessional valuing and socialization, team skills, and professional development, including the interrelationship between these 3 areas.

Method: A cross-sectional survey-based pre-post design was utilized across 4 cohorts of students participating in the training program from 2018 through 2021.

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Objectives: A male is less adaptable to biological stressors than a female fetus with consequent higher morbidity and mortality. Adverse birth outcomes increase and male livebirths decrease after environmental disasters, economic crises, and terrorist events. We hypothesized the ratio of male to female livebirths would decrease in areas affected by severe tropical cyclones (TCs) in Queensland, Australia.

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Transmission of Ross River virus (RRV) is influenced by climatic, environmental, and socio-economic factors. Accurate and robust predictions based on these factors are necessary for disease prevention and control. However, the complicated transmission cycle and the characteristics of RRV notification data present challenges.

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Background: In a cohort of adults with intellectual disability who were followed for up to 16-years, we investigated characteristics associated with frequent emergency department (ED) presentations, hospitalisation, and psychiatric care.

Method: Community-dwelling adults with intellectual disability residing in Queensland, Australia, were followed from 1999 to 2015. Healthcare presentations were extracted from administrative databases.

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Objective: Investigate an association between severe tropical cyclones (TCs) and birth outcomes in an Australian population.

Methods: We analysed over 600,000 singleton livebirths collected through the Queensland Perinatal Data Collection between 2008 and 2018. We estimated the odds ratios (ORs) of adverse birth outcomes using logistic multi-level modelling.

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Article Synopsis
  • Leadbeater's possum is a critically endangered marsupial found mainly in the Victorian Central Highlands of Australia, with a small unique population in lowland swamp forests.
  • This study investigates ectoparasites (fleas, ticks, and mites) associated with the possums during translocation efforts, revealing significant differences in flea species between highland and lowland habitats.
  • The findings highlight potential risks of introducing highland fleas to lowland populations during translocations, emphasizing the need for careful monitoring to manage these risks.
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Background: Dengue (DENV), Ross River (RRV) and Barmah Forest viruses (BFV) are the most common human arboviral infections in Australia and the Pacific Island Countries and Territories (PICTs) and are associated with debilitating symptoms. All are nationally notifiable in Australia, but routine surveillance is limited to a few locations in the PICTs. Understanding the level of human exposure to these viruses can inform disease management and mitigation strategies.

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Purpose: Recently, the literature has witnessed a surging interest regarding the use of mind-body approaches with people who have aphasia, generating a plethora of possible outcome measures. During this same time, a core outcome set for aphasia has been recommended. The purpose of this clinical focus article is to give our survivor, co-survivor, and clinician stakeholder coauthors a platform to share their personal narrative regarding their yoga journey, with the goal of identifying primary outcome domains central to capturing the impact of yoga on the recovery process for people with poststroke aphasia.

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Ross River virus (RRV), the most common human arbovirus infection in Australia, causes significant morbidity and substantial medical costs. About half of Australian cases occur in Queensland. We describe the spatial and temporal patterns of RRV disease in Queensland over the past two decades.

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Background: Global annual reports of visceral leishmaniasis or kala-azar ("black fever") reduced from 200,000 cases in 2012 to 23,804 in 2015. India, Bangladesh and Nepal reported 80% of the global cases in 2012, but 39% in 2015. We sought to identify major amenable barriers to early diagnosis of kala-azar in peripheral areas of Mymensingh district, an area of Bangladesh that was highly endemic for kala-azar.

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  • The Leadbeater's possum is a critically endangered marsupial native to south-eastern Australia, with limited knowledge about its health and mortality.
  • A study in June 2019 involved the examination of a deceased male Leadbeater's possum, revealing microfilariae (a type of parasitic worm) in various organs but no significant health issues aside from minor skin damage.
  • The identified filarioid nematode species is known to affect other Australian marsupials and rodents, suggesting the possum serves as a natural host for the parasite.
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