Publications by authors named "Harita Vadari"
Article Synopsis
- The study investigates how adverse childhood experiences (ACEs), specifically parental substance abuse and physical abuse, impact cognitive health in older adults, using a comprehensive set of neuropsychological tests.
- It analyzed data from over 3,300 older adults and identified that parental substance abuse correlated with poorer cognitive function through factors like education and stroke, while parental physical abuse affected cognition mainly through stroke.
- The findings suggest long-lasting effects of these ACEs on cognitive aging and highlight the need for further research on other ACEs and their potential intervention strategies.
Background: The Diabetes Prevention Program (DPP) and metformin can prevent or delay the onset of type 2 diabetes mellitus (T2DM) among patients with prediabetes. Yet, even when these evidence-based strategies are accessible and affordable, uptake is low. Thus, there is a critical need for effective, scalable, and sustainable approaches to increase uptake and engagement in these interventions.
View Article and Find Full Text PDFObjective: Alzheimer disease (AD) is a common and costly neurodegenerative disorder. A large proportion of AD risk is heritable, and many genetic risk factors have been identified. The objective of this study was to test the hypothesis that cumulative genetic risk of known AD markers contributed to odds of dementia in a population-based sample.
View Article and Find Full Text PDFAlzheimer's disease and related dementias lack effective treatment or cures and are major public health challenges. Risk for Alzheimer's disease and related dementias is partially attributable to environmental factors. The heavy metals lead, cadmium, and manganese are widespread and persistent in our environments.
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