Publications by authors named "Harish Sulekar"
Article Synopsis
- The study investigates the use of skin autofluorescence (SAF) as a noninvasive method to assess the risk of diabetic foot ulcers (DFUs) by measuring levels of advanced glycation end products in tissue.* -
- A total of six studies, involving 611 participants, were analyzed, showing that SAF levels were significantly higher in patients with DFUs compared to those without, indicating a strong association with DFU risk.* -
- The results suggest that SAF could be a valuable tool for predicting DFU risk, but the authors emphasize the need for more research to confirm its effectiveness for diagnosis and prognosis.*
Background: This systematic review and meta-analysis were aimed to study the association of tissue accumulation of advanced glycation end products (AGEs) measured as skin autofluorescence (SAF) with cardiovascular disease (CVD), cardiovascular mortality (CVM) and all-cause mortality (ACM) in hemodialysis (HD) patients.
Methods: All major databases were searched for relevant studies reporting SAF in dialysis patients. Data for meta-analyses were extracted in the form of odds ratios (OR) and/or hazard ratios (HR) and the pooled overall outcomes were computed for the association of SAF with CVD, CVM, ACM in HD patients using either fixed or random effects meta-analysis based on the between-study heterogeneity.