Publications by authors named "Haris Zia"
Article Synopsis
- A cardiac septal occluder (CSO) can be used endoscopically to treat tracheoesophageal fistula (TEF), particularly in complex cases.
- This case study discusses a patient with metastatic cervical cancer who developed a malignant TEF due to direct invasion of the trachea, despite prior treatment with radiotherapy and stenting.
- The use of a PFO occluder as a palliative measure effectively closed the TEF, helping to prevent aspiration pneumonia and enhance the patient's quality of life.
Host inflammatory responses predict worse outcome in severe pneumonia, yet little is known about what drives dysregulated inflammation. We performed metagenomic sequencing of microbial cell-free DNA (mcfDNA) in 83 mechanically ventilated patients (26 culture-positive, 41 culture-negative pneumonia, 16 uninfected controls). Culture-positive patients had higher levels of mcfDNA than those with culture-negative pneumonia and uninfected controls (p<0.
View Article and Find Full Text PDFBackground: Metagenomic sequencing of respiratory microbial communities for pathogen identification in pneumonia may help overcome the limitations of culture-based methods. We examined the feasibility and clinical validity of rapid-turnaround metagenomics with Nanopore™ sequencing of clinical respiratory specimens.
Methods: We conducted a case-control study of mechanically-ventilated patients with pneumonia (nine culture-positive and five culture-negative) and without pneumonia (eight controls).