Publications by authors named "Haris Zia"

Article Synopsis
  • A cardiac septal occluder (CSO) can be used endoscopically to treat tracheoesophageal fistula (TEF), particularly in complex cases.
  • This case study discusses a patient with metastatic cervical cancer who developed a malignant TEF due to direct invasion of the trachea, despite prior treatment with radiotherapy and stenting.
  • The use of a PFO occluder as a palliative measure effectively closed the TEF, helping to prevent aspiration pneumonia and enhance the patient's quality of life.
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Host inflammatory responses predict worse outcome in severe pneumonia, yet little is known about what drives dysregulated inflammation. We performed metagenomic sequencing of microbial cell-free DNA (mcfDNA) in 83 mechanically ventilated patients (26 culture-positive, 41 culture-negative pneumonia, 16 uninfected controls). Culture-positive patients had higher levels of mcfDNA than those with culture-negative pneumonia and uninfected controls (p<0.

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Background: Metagenomic sequencing of respiratory microbial communities for pathogen identification in pneumonia may help overcome the limitations of culture-based methods. We examined the feasibility and clinical validity of rapid-turnaround metagenomics with Nanopore™ sequencing of clinical respiratory specimens.

Methods: We conducted a case-control study of mechanically-ventilated patients with pneumonia (nine culture-positive and five culture-negative) and without pneumonia (eight controls).

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