Airborne fungal spores in Ahwaz, Iran.

A one-year study of airborne fungi in Ahwaz, Iran, indicated that opportunistic fungi of clinical significance varied in response to environmental conditions. Saprophytic strains did not vary significantly. The most prevalent airbone fungi were Penicillium, Alternaria, Aspergillus and Cladosporium.

Resistance of staphylococci to penicillin-G and cloxacillin.

Staphylococcus aureus and epidermidis species from patient cultures and hospital environmental samples were studied for resistance to Penicillin-G and Cloxacillin, a penicillinase resistant penicillin. Only 4--7% of the 232 Staphylococcus aureus strains were sensitive to Penicillin-G; 40--41% were sensitive to Cloxacillin. Patient strains (57) of Staphylococcus epidermidis were sensitive to Penicillin-G in 29% and to Cloxacillin in 53% of the cases.

Comparative study of trichothecin, amphotericin B, and 5-fluorocytosine against Cryptococcus neoformans in vitro and in vivo.

Trichothecin (T-cin), amphotericin B (AB), and 5-fluorocytosine (FC) were compared singly and in combination for capacities to inhibit growth of Cryptococcus neoformans in culture and to protect mice bearing infections with this yeast. The minimum inhibitory concentrations for T-cin, AB, and FC were found to be 0.5, 0.

In vitro and in vivo activity of 2,4-diamino-6-(2-(3,4-dichlorophenyl)acetamido) quinazoline against Cryptococcus neoformans.

The minimum inhibitory concentration of quinazoline derivative was determined by the tube dilution method for Cryptococcus neoformans, strain 184. The effect of this chemical agent on macromolecular metabolism indicated an inhibition of incorporations of labeled precursors into RNA and protein of C. neoformans.