A Cortico-Striatal Circuit for Sound-Triggered Prediction of Reward Timing.

A crucial aspect of auditory perception is the ability to use sound cues to predict future events and to time actions accordingly. For example, distinct smartphone notification sounds reflect a call that needs to be answered within a few seconds, or a text that can be read later; the sound of an approaching vehicle signals when it is safe to cross the street. Other animals similarly use sounds to plan, time and execute behaviors such as hunting, evading predation and tending to offspring.

Enhanced stability of complex sound representations relative to simple sounds in the auditory cortex.

Typical everyday sounds, such as those of speech or running water, are spectrotemporally complex. The ability to recognize complex sounds (CxS) and their associated meaning is presumed to rely on their stable neural representations across time. The auditory cortex is critical for processing of CxS, yet little is known of the degree of stability of auditory cortical representations of CxS across days.