Publications by authors named "Harini Sundar"
Article Synopsis
- - Hepatocellular Carcinoma (HCC) is the main type of liver cancer that results from issues with cell cycle regulation, with higher expression of Heat Shock Protein 90 (HSP90) and mitochondrial HSP90 (TRAP1) noted in patients.
- - The review highlights the significance of HSP90 and TRAP1 inhibitors and their targeted delivery for potential early diagnosis and treatment of HCC.
- - It emphasizes the role of protein-protein interactions involving HSP90 and TRAP1 in HCC pathways, while exploring systems and computational biology to study the effects of herbal plant molecules on these proteins.
Objective: To compare the clinical presentation, risk factors and outcomes of young patients (≤45 years) presenting with ST segment-elevation myocardial infarction (STEMI) with older STEMI patients in the Tamil Nadu STEMI program (TN-STEMI).
Methods: A total of 2,420 patients were enrolled in the TN-STEMI program, which is a pre-implementation and post-implementation quality of care study. The cohort of patients was divided into young STEMI patients (≤45 years) and compared with those aged >45 years.