Publications by authors named "Harini Rajgopal Bala"
Melasma is a common disorder of hyperpigmentation that presents a therapeutic challenge for clinical dermatologists. The pathogenesis is complex, but previous studies have demonstrated vascular proliferation is a key factor in the development of the classic hyperpigmented patches. Studies have revealed reduction of erythema by oral tranexamic acid; however, there has been no direct comparison to placebo.
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- The study aimed to evaluate if nickel-sensitized individuals would react to high nickel-releasing metal discs during short, repetitive patch tests, as per the European Chemical Agency's definition.
- Out of 45 individuals tested, nickel release from the discs exceeded safety limits, but only one person showed a significant allergic reaction.
- Most participants did not react after 30 minutes of exposure over two weeks, suggesting that longer exposure times are needed to fully understand how nickel triggers allergic contact dermatitis in sensitive individuals.
Chlorhexidine is a widely used and effective antiseptic agent. Although skin contact is usually well tolerated, it may cause both immediate and delayed hypersensitivity reactions. We report a case of immediate hypersensitivity to chlorhexidine causing both skin and respiratory symptoms following occupational exposure to chlorhexidine in a health-care worker.
View Article and Find Full Text PDFWe report two cases of Caucasian women who developed folliculocentric pustulosis after exposure to amoxycillin. A literature review found that most amoxycillin-related pustular eruptions were reported as acute generalised exanthematous pustulosis (AGEP) or acute localised exanthematous pustulosis (ALEP). Histopathology from both our cases showed sterile suppurative folliculitis, which resolved on the cessation of amoxycillin.
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