Publications by authors named "Harikumar S Kartha"

Chemical acaricides are widely used for the effective control of ticks in India. The synthetic pyrethroids, are one of the most popular chemical acaricides with selective neurotoxic potential. Flumethrin is a type II synthetic pyrethroid used extensively in veterinary practice in India.

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In the present study, the cytotoxic effects of amitraz, an octopamine receptor agonist on the reproductive system of engorged adult females of Rhipicephalus (Boophilus) annulatus were assessed using histology, electron microscopy and octopamine beta (OCTβ) receptor transcriptional expression analysis. Adult immersion test (AIT) was performed by immersing the fully engorged female ticks for 2 min in different concentrations of amitraz (200, 250, 300, 350 ppm). Amitraz at the dose of 300 ppm, caused an adult tick mortality of 16.

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Article Synopsis
  • The study investigates the effects of insecticides deltamethrin and amitraz on the reproductive cells of fully engorged female Rhipicephalus (Boophilus) annulatus ticks using ultrastructural analysis.
  • It discovered that untreated ticks' ovaries had oocytes at various developmental stages, characterized by distinct cell membranes and structures, while degenerative changes began five days post-engorgement.
  • Deltamethrin caused more severe damage to oocytes compared to amitraz, leading to changes such as wrinkling, nuclear membrane inconsistencies, and mitochondrial swelling.
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