Publications by authors named "Harikrishnan M"

Plastic pots used in horticultural nurseries generate substantial waste, causing environmental pollution. This study aimed to develop biodegradable composites from banana pseudo-stem reinforced with agricultural residues like pineapple leaves, taro and water hyacinth as eco-friendly substitutes. The aim of this study is to develop optimised banana biocomposite formulations with suitable reinforcements that balance mechanical durability, biodegradation, and seedling growth promotion properties to serve as viable eco-friendly alternatives to plastic seedling pots.

View Article and Find Full Text PDF

Limnocharis flava is a noxious aquatic weed that poses a threat to paddy cultivation. The high cellulose and low lignin contents in this plant make it a potential raw material for papermaking. Against this backdrop, this study was taken up to develop Limnocharis flava (LF) based sheets containing natural fibres from Banana (B), Pineapple (P), and Rice Straw (RS) as reinforcing agents.

View Article and Find Full Text PDF
Article Synopsis
  • The study assessed trace metal levels in sediments of mangrove ecosystems in Kerala, revealing high concentrations particularly of Cu, Cr, and Ni, which exceed safety guidelines and pose ecological risks.
  • Principal component analysis indicated that industrial activities and urban waste significantly contribute to this metal contamination, with cadmium being the most concerning for the mangrove ecosystem at Vypin.
  • Avicennia marina was found to effectively accumulate and translocate these metals, suggesting its potential use for phytoremediation to help mitigate contamination in coastal areas.
View Article and Find Full Text PDF

Endophytic fungi from marine macroalgae are endowed with various pharmacologically active metabolites. This study mined, identified and screened endophytic fungi (EF) isolated from marine algae from the west coast of South India for screening anticancer, antioxidant and antimicrobial secondary metabolite producers. Five EF isolated from sampled marine algae were identified using morphology and ITS based identification as and After culturing 20 days on PDA medium, the ethyl acetate extracts of showed potent antimicrobial activity against with an IC value of 458.

View Article and Find Full Text PDF

Arid/semi-arid and coastal agricultural areas of the world are especially vulnerable to climate change-driven soil salinity. Salinity tolerance in plants is a complex trait, with salinity negatively affecting crop yield. Plants adopt a range of mechanisms to combat salinity, with many transporter genes being implicated in Na-partitioning processes.

View Article and Find Full Text PDF

The global emergence of antimicrobial resistance (AMR) among pathogens is a major public health crisis that might soon lead to a post-antibiotic era. Klebsiella pneumoniae, included in the World Health Organization list of critical priority pathogens, is an emerging threat to global health owing to the rapid rise of convergent AMR and hypervirulent strains. Comprehensive epidemiology of AMR-hypervirulent determinants in K.

View Article and Find Full Text PDF
Article Synopsis
  • The COVID-19 pandemic has caused a global crisis, prompting urgent research for new antiviral treatments as existing options are limited and the SARS-CoV-2 virus spreads rapidly.
  • This study investigates the potential of marine algal compounds to inhibit the virus's entry and replication using molecular docking analysis, focusing on key targets in the virus's lifecycle like spike glycoprotein and 3-chymotrypsin-like protease.
  • Results highlight several marine algal compounds, such as κ-carrageenan and eckol, showing promising binding scores against SARS-CoV-2 targets, suggesting their potential as effective treatments after further testing and validation.
View Article and Find Full Text PDF

The sensitive and selective detection of nitroexplosive molecules thorough a simple methodology has received a significant field of research affecting global security and public safety. In the present study, the synthesis of anthracene-based chalcone (S1) was conducted using a simple condensation method. S1 was found to exhibit unique properties, such as aggregation-induced emission in solution and mechanochromic behavior in solid state.

View Article and Find Full Text PDF

Introduction: Although abnormalities of ventricular repolarization are a hallmark of SC, their clinical impact on management remains to be determined. This study sought to evaluate the prognostic value of dispersion of repolarization in stress cardiomyopathy (SC) with regards to major cardiac events (MCE), recovery time, and recurrence.

Methods: This study analyzed data from258 patients with SC, from January 2009 to January 2018.

View Article and Find Full Text PDF

Three types of novel star-shaped molecular architectures, D-π-D-π-D and (D-π)-D-(π-D) anthracene (ANTTPA, AOME, AOHE) based hole transporting materials, are designed for hybrid perovskite solar cells using the Gaussian 09 computation program with the B3LYP/6-31g (d, p) basis set level. The HOMO energy level of the designed materials has a higher HOMO energy level compared to the perovskite HOMO energy level, which is more facile for hole transport from the hole transporting layer to the oxidized perovskite layer. Thereafter, anthracene-based derivatives were synthesized from Buchwald-Hartwig and Mizoroki-Heck cross coupling reactions.

View Article and Find Full Text PDF

The feeding strategy, overlap and trophic interactions of four demersal catfishes inhabiting Cochin Estuary, Arius maculatus (n = 67), A. subrostratus (n = 63), A. arius (n = 21) and Mystus gulio (n = 69) were investigated through gut-content analyses.

View Article and Find Full Text PDF

The synthesis and optical studies of salicylate based azo derivatives (DPSAD and IPSAD) are reported. The receptors act as a versatile fluorogenic chemosensor for Zn causing a selective enhancement of fluorescence over other competing cations. The complex formed between receptors and Zn are identified on the basis of absorption and fluorescence titration and further confirmed by ESI-MS.

View Article and Find Full Text PDF

Background: Risk stratification in Brugada syndrome remains a controversial and unresolved clinical problem, especially in asymptomatic patients with a type 1 ECG pattern. The purpose of this study is to derive and validate a prediction model based on clinical and ECG parameters to effectively identify patients with a type 1 ECG pattern who are at high risk of major arrhythmic events (MAE) during follow-up.

Methods: This study analysed data from 103 consecutive patients with Brugada Type 1 ECG pattern and no history of previous cardiac arrest.

View Article and Find Full Text PDF

Fragmented QRS (fQRS) and Q waves are ECG findings in patients with myocardial scar. fQRS is more sensitive than pathological Q waves in detecting myocardial fibrosis in patients with coronary artery disease (CAD). Cardiac magnetic resonance (CMR) imaging is used for the diagnosis and for quantifying scar tissue in patients with HCM.

View Article and Find Full Text PDF

Objective: To assess the sanitary condition and water quality of household wells and to depict it spatially using Geographic Information System (GIS) in an urban area of Trivandrum, Kerala state, India.

Study Design: A community-based cross-sectional census-type study.

Methods: Study was conducted in an urban area of Trivandrum.

View Article and Find Full Text PDF

Caridea, an infraorder of shrimps coming under Pleocyemata was first reported from the oceans before 417 million years followed by their radiation recorded during the Permian period. Hitherto, about 3877 extant caridean species were accounted within which one quarter constitute freshwater species. Freshwater prawns of genus Macrobrachium (Infraorder Caridea; Family Palaemonidae), with more than 240 species are inhabitants of diverse aquatic habitats like coastal lagoons, lakes, tropical streams, ponds and rivers.

View Article and Find Full Text PDF

Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them.

View Article and Find Full Text PDF

Pseudodiaptomus binghami Sewell, 1912 was first described from the Rangoon River (now Yangon River) estuary, Myanmar. Pseudodiaptomus malayalus Wellershaus, 1969 previously known as P. binghami malayalus, is a typical brackish-water calanoid copepod from Cochin Estuary, Kerala.

View Article and Find Full Text PDF

Introduction: Risk stratification of asymptomatic patients with a Brugada type 1 ECG pattern remains an unresolved clinical conundrum. In contrast to provocative pharmacological testing in Brugada syndrome, there is limited data on the role of exercise stress testing as a risk stratification modality. The objective of this study was to evaluate the utility of exercise testing in asymptomatic patients with type 1 Brugada pattern to prognosticate major arrhythmic events (MAE) during follow-up.

View Article and Find Full Text PDF

Background: Atrioventricular (AV) block is rare in Takotsubo cardiomyopathy (TC).

Case Report: A 66-year-old female presented with fatigue. Her electrocardiogram revealed 3:2 Mobitz Type II AV block, confirmed to be supra-Hisian by electrophysiological study.

View Article and Find Full Text PDF

The occurrence of pre-excitation in tricuspid atresia (TA) is slightly more common than that in normal children. The accessory pathway (AP), when it occurs in the setting of congenital atrioventricular valvar disease, is usually ipsilateral to the side of the abnormal valve. This report describes a patient with TA who had pre-excitation due to a left-sided AP that masked and modified the typical electrocardiographic features.

View Article and Find Full Text PDF

Morphological identification of the marine cyclopoid copepod Dioithona rigida in combination with sequencing a 645 bp fragment of mitochondrial cytochrome oxidase c subunit I (mtCOI) gene, collected from offshore waters of Kavarathi Island, Lakshadweep Sea, is presented in this study. Kiefer in 1935 classified Dioithona as a separate genus from Oithona. The main distinguishing characters observed in the collected samples, such as the presence of well-developed P5 with 2 setae, 5 segmented urosome, 12 segmented antennule, compact dagger-like setae on the inner margin of proximal segment of exopod ramus in P1-P4 and engorged portion of P1-bearing a spine, confirmed their morphology to D.

View Article and Find Full Text PDF