Multifaceted bioactivity of marine fungal derived secondary metabolite, xyloketal B -a review.

Background: A growing number of findings have focused on the distinctive physiochemical characteristics that marine microorganisms have acquired as a result of their adaptation to the challenging conditions inherent in the marine environment. It has been established that the marine environment is a very rich source of bioactive substances with a variety of biological effects and structural diversity. A major discovery was the extraction of xyloketals from sp.

Mechanism of protection of rat hepatocytes from acetaminophen-induced cellular damage by ethanol extract of .

The aim of this study is to evaluate the protective effect of ethanol extract of (EEAL) in preventing acetaminophen induced liver toxicity. EEAL was prepared and its hepatoprotective effect was studied in both isolated primary hepatocytes and in Sprague Dawley rats . For studies, the animals were grouped as Group I - Control; Group II - ACN (2 g/kg b.