Publications by authors named "Hari R Nair"
Kidney Med
September 2024
Article Synopsis
- A retrospective study analyzed metabolic differences between pure and impure uric acid kidney stone formers using data from patients at Yale Urology and Nephrology Clinics between 1996 and 2021.
- Among 722 uric acid stone formers (16.8% of the total), pure stone formers were generally older, heavier, and had a higher incidence of chronic kidney disease.
- The study found that pure uric acid stone formers had lower urinary pH and citrate levels, along with higher protein intake markers, indicating that adjusting protein consumption might help lower the risk of stone formation, especially in those with kidney issues.
Am J Nephrol
November 2023
Article Synopsis
- Kidney stone composition varies with factors like age, sex, and renal function, particularly indicated by eGFR, which influences urine chemistry.
- A study of 811 kidney stone patients from Yale Medicine found that lower eGFR correlates with an increase in uric acid stones and a decrease in calcium stones, along with significant changes in urine parameters like pH and mineral content.
- The findings suggest that renal function is important in understanding and managing kidney stone risks, indicating that prevention strategies may need to adjust based on a patient's kidney function and available urine or stone analysis data.
