World's longest surviving liver-pancreas recipient.

In July 1988, the liver and pancreas of a cadaveric donor were transplanted separately into a man with type 1 diabetes with end-stage chronic hepatitis B virus. Two features of the operation may help explain the patient's current status as the longest-lived liver-pancreas recipient. One was enteric drainage of pancreatic exocrine secretions.

Gastric retention of enteric-coated sulfasalazine tablets. A complication of gastroduodenal Crohn's disease.

A case is described in which a patient with known gastroduodenal Crohn's disease developed a picture of gastric outlet obstruction accompanied by gastric retention of many enteric-coated sulfasalazine tablets. The tablets were removed by gastric lavage with a sodium bicarbonate solution. Following this observation, an in vitro study was done in which the rate of disintegration of enteric-coated sulfasalazine tablets was found to be directly related to pH.

Gastroduodenal Crohn's disease. Differential diagnosis and treatment.

Gastroduodenal Crohn's disease usually, but not always, occurs in patients with previously established ileal and/or colonic Crohn's disease. Symptoms include postprandial epigastric pain accompanied by nausea and sometimes vomiting, weight loss, anorexia, bloating, and diarrhea. Obstruction is the most common complication.

Sweet's syndrome associated with rheumatoid arthritis.

A case of Sweet's syndrome (acute febrile neutrophilic dermatosis) is reported in a patient with long-standing rheumatoid arthritis. Although Sweet's syndrome has been described in association with leukemias, other malignancies, and a variety of inflammatory disorders, it has not been associated with rheumatoid arthritis. Sweet's syndrome is reviewed with regard to pathogenesis and associated diseases.