Impact of Classical and Quantum Light on Donor-Acceptor-Donor Molecules.

Investigations of entangled and classical two-photon absorption have been carried out for six donor (D)-acceptor (A)-donor (D) compounds containing the dithieno pyrrole (DTP) unit as donor and acceptors with systematically varied electronic properties. Comparing ETPA (quantum) and TPA (classical) results reveals that the ETPA cross section decreases with increasing TPA cross section for molecules with highly off-resonant excited states for single-photon excitation. Theory (TDDFT) results are in semiquantitative agreement with this anticorrelated behavior due to the dependence of the ETPA cross section but not TPA on the two-photon excited state lifetime.

Linear and Nonlinear Optical Properties of All- and All- Poly(-phenylenevinylene).

Poly(-phenylenevinylene) (PPV) is a staple of the family of conjugated polymers with desirable optoelectronic properties for applications including light-emitting diodes (LEDs) and photovoltaic devices. Although the significant impact of olefin geometry on the steady-state optical properties of PPVs has been extensively studied, PPVs with precise stereochemistry have yet to be investigated using nonlinear optical spectroscopy for quantum sensing, as well as light harvesting for biological applications. Herein, we report our investigation of the influence of olefin stereochemistry on both linear and nonlinear optical properties through the synthesis of all- and all- PPV copolymers.

and analysis of enoyl acyl carrier protein reductase - A possible drug target.

The emergence of increased resistance to the available drugs has created a situation that demands to find out more specific molecular drug targets for Leishmaniasis. The enoyl acyl carrier protein reductase (ENR), a regulatory enzyme in type II fatty acid synthesis, was confirmed as a novel drug target and triclosan as its specific inhibitor in many microorganisms. In this study, the triclosan was tested for the leishmanicidal property against () and the results of and drug assays on promastigotes and amastigotes showed that triclosan possessed antileishmanial activity with a half minimal inhibitory concentration (IC) of 30 µM.

Validation of NAD synthase inhibitors for inhibiting the cell viability of : and approach.

NAD (nicotinamide adenine dinucleotide) synthase catalyses the biochemical synthesis of NAD, from nicotinic acid adenine dinucleotide (NAAD). NAD may be synthesized through the pathways and/or the salvage pathways in cells. However, in parasite, the synthesis of NAD solely depends on the salvage pathways.

Excitation-dependent electron exchange energy and electron transfer dynamics in a series of covalently tethered N,N-bis(4'-tert-butylbiphenyl-4-yl)aniline - [C] fullerene dyads via varying π-conjugated spacers.

Femtosecond time-resolved fluorescence and transient absorption studies are reported for three newly synthesized covalently linked N,N-bis(4'-tert-butylbiphenyl-4-yl)aniline (BBA) and pyrrolidinofullerenes (C60)-based donor-π conjugated bridge-acceptor dyads (D-B-A) as functions of the bridge length (7.1, 9.5 and 11.

Photoinduced bimolecular electron transfer from aromatic amines to pentafluorophenyl porphyrin combined with ultrafast charge recombination persistence with Marcus inverted region.

The dynamics of photoinduced bimolecular reductive electron transfer between meso-tetrakis(pentafluorophenyl)porphyrin (HFTPP), an acceptor (A), and five aromatic amines (donor (D)) with varying oxidation potentials (aniline (AN), N-methylaniline (MAN), N-ethylaniline (EAN), N,N-dimethylaniline (DMAN) and N,N-diethylaniline (DEAN)) in dichloromethane (DCM) as a solvent as well as in neat donor solvents were investigated by employing nanosecond to femtosecond time-resolved fluorescence spectroscopy and femtosecond time-resolved transient absorption spectroscopy upon S excitation of HFTPP. Systematic studies of time-resolved fluorescence quenching dependent on the donor concentration in the concentration range of 0.01-2 M and finally in neat donor solvents broadly enabled us to determine the electron transfer dynamics in three regimes of electron transfer: stationary or diffusion-controlled electron transfer, non-stationary electron transfer and intrinsic or ultrafast electron transfer.