Lower chlorinated PCBs accumulate in demolition workers while working on a contaminated worksite.

Several buildings in a Danish social housing estate exceeded indoor air guidance values for polychlorinated biphenyls (PCBs), leading to their demolition. Here, we conducted a biomonitoring study among the workers on-site (n = 24) to evaluate their exposure to all 209 PCBs across the two-year demolition. We compared their PCB serum concentrations and accumulation to those of demolition workers at other worksites (n = 21) and office workers (n = 17).

Assessing the efficacy of a German-inspired intervention on occupational contact dermatitis in Denmark: A randomised controlled trial with 3-month follow-up.

Background: Occupational contact dermatitis (OCD) is a prevalent, often chronic disease that poses a risk for job loss and decreased quality of life. In Germany, a multi-step prevention programme emphasising early detection and highly specialised multidisciplinary treatment has been implemented with great success.

Objectives: To examine the effectiveness of a Danish-adapted version of the German prevention effort on OCD severity, quality of life and occupational consequences at 3-month follow-up.

Impact of atopic dermatitis on occupational contact dermatitis among young people: A retrospective cohort study.

Background: Occupational contact dermatitis (OCD) is a common occupational disease. Atopic dermatitis (AD) is a known risk factor for OCD.

Objectives: To determine the prevalence of previously diagnosed AD among young workers with recognized OCD and assess its impact on OCD prognosis.

Exposure to airborne polychlorinated biphenyls and type 2 diabetes in a Danish cohort.

Background: Previous research indicates an association between higher-chlorinated polychlorinated biphenyls (PCBs) and type 2 diabetes (T2D). However, less is known about the extent to which PCB exposure in indoor air, composed primarily of lower-chlorinated PCBs, affects T2D risk. We assessed the association between indoor air exposure to PCBs in residential buildings and T2D incidence.

The Relationship Between Potential Occupational Sensitizing Exposures and Asthma: An Overview of Systematic Reviews.

Objectives: The aim was to identify, appraise, and synthesize the scientific evidence of the relationship between potential occupational sensitizing exposures and the development of asthma based on systematic reviews.

Methods: The study was conducted as an overview of systematic reviews. A systematic literature search was conducted for systematic reviews published up to 9 February 2020.

Cancer Risk following Residential Exposure to Airborne Polychlorinated Biphenyls: A Danish Register-Based Cohort Study.

Background: Polychlorinated biphenyls (PCBs) are biopersistent chemicals classified as human carcinogens. This classification is primarily based on evidence on higher-chlorinated PCBs found in food. The carcinogenic potential of airborne lower-chlorinated PCBs remains largely unexplored.

Historical Asbestos Measurements in Denmark-A National Database.

Objectives: Due to the long lag-time for health outcomes, historical asbestos exposure measurements are valuable to support assessments of associated occupational health effects, and also to assess time trends and effects of preventive measures.

Methods: Different sources of stored data were collated, assessed and refined to create a harmonized database on historical asbestos fibre concentrations measured in specific work tasks and different industries. The final database contains 9236 asbestos measurements from Danish workplaces collected from 1971 to 1997.

Occupational contact dermatitis among young people in Denmark - A survey of causes and long-term consequences.

Background: Studies on the causes and consequences of occupational contact dermatitis (OCD) among young workers are non-existent.

Objectives: Determine causes and consequences of OCD among workers younger than 35 years of age.

Methods: A questionnaire was sent to 6251 workers younger than 35 years at notification with recognized OCD (response rate 47%).

Maternal exposure to airborne polychlorinated biphenyls (PCBs) and risk of adverse birth outcomes.

Human health effects of airborne lower-chlorinated polychlorinated biphenyls (LC-PCBs) are largely unexplored. Since PCBs may cross the placenta, maternal exposure could potentially have negative consequences for fetal development. We aimed to determine if exposure to airborne PCB during pregnancy was associated with adverse birth outcomes.

Asthma-inducing potential of 28 substances in spray cleaning products-Assessed by quantitative structure activity relationship (QSAR) testing and literature review.

Exposure to spray cleaning products constitutes a potential risk for asthma induction. We set out to review whether substances in such products are potential inducers of asthma. We identified 101 spray cleaning products for professional use.

Incidence rates of occupational contact dermatitis in Denmark between 2007 and 2018: A population-based study.

Background: Recent population-based studies on the incidence rates (IRs) of occupational contact dermatitis (OCD) are sparse.

Objectives: To determine the IRs of OCD and development thereof between 2007 and 2018 in known risk occupations.

Methods: Data on all recognized cases of OCD were used to calculate IRs as the number of recognized OCD cases per 10 000 workers per year.

Degree of employment, sick leave, and costs following notification of occupational contact dermatitis-A register-based study.

Background: Occupational contact dermatitis (OCD) is the most commonly recognized occupational disease in Denmark.

Objectives: To examine the impact of recognized OCD on degree of employment, sick leave, unemployment, and job change.

Methods: Data on all recognized individuals with OCD notified in Denmark between 2010 and 2015 (n = 8940) were linked to information on social transfer payments in the years before and after notification.

Chemicals inhaled from spray cleaning and disinfection products and their respiratory effects. A comprehensive review.

Spray cleaning and disinfection products have been associated with adverse respiratory effects in professional cleaners and among residents doing domestic cleaning. This review combines information about use of spray products from epidemiological and clinical studies, in vivo and in vitro toxicological studies of cleaning chemicals, as well as human and field exposure studies. The most frequent chemicals in spray cleaning and disinfection products were compiled, based on registrations in the Danish Product Registry.

[Work-up of asbestosis and estimation of asbestos exposure in an occupational context].

Asbestosis is interstitial lung fibrosis due to inhalation of asbestos fibres. Up to the ban of import in 1986, 0.7 mil tons had been used in Denmark.

[Specific bronchial and nasal provocations with work-related allergens].

Specific inhalation challenge (SIC) is the golden standard for identifying specific causes of work-related asthma and rhinoconjunctivitis. Few centres offer SIC as it requires experience, resources and acute treatment facilities. Prior to SIC treatment should be carefully reduced.

Plasma polychlorinated biphenyls in residents of 91 PCB-contaminated and 108 non-contaminated dwellings-an exposure study.

Background: In the1950s-1970s polychlorinated biphenyls (PCBs) were used in several countries as plasticizers in elastic sealants in buildings.

Objective: The primary objective was to study whether residents of PCB-contaminated dwellings had higher plasma levels of PCBs than their neighbours in non-contaminated dwellings. The secondary objective was to study possible associations between concentrations of PCBs in the indoor air and in the plasma of residents.

Polychlorinated biphenyls (PCBs) in indoor air originating from sealants in contaminated and uncontaminated apartments within the same housing estate.

Twenty-four congeners of polychlorinated biphenyls (PCBs) were measured in 83 air samples and 20 elastic sealants samples of apartments with PCB-containing sealants. In addition, PCBs were measured in 21 air samples from reference apartments located in an uncontaminated section of the same estate. The PCB(tot) levels in the air of the contaminated section were 168-3843 ng m(-3) (mean: 1030 ng m(-3)), while the mean levels in the reference apartments were 6.

Moulds in floor dust - a particular problem in mechanically ventilated rooms? A study of adolescent schoolboys under the Danish moulds in buildings program.

Objective: To test the hypothesis that the association between levels of mould in floor dust and prevalence of potentially building-related symptoms may depend on the type of ventilation.

Methods: This stratified cross-sectional study is part of the Danish moulds in buildings program (DAMIB), including 503 adolescent schoolboys aged 13-17 years at 15 schools. Besides assessing symptom prevalences in questionnaires, we measured numerous potential risk factors in the school buildings.

Occupational rhinosinusitis due to etoposide, an antineoplastic agent.

Objective: This paper reports a rare case of an occupational hypersensitivity reaction to an antineoplastic agent.

Methods: This is a clinical case report of a 45-year-old nurse who developed throat irritation and chronic nasal congestion followed by sinusitis shortly after beginning work at an oncological out-patient clinic. The symptoms disappeared upon leaving the clinic two years later, but they returned when she resumed work at the oncology unit at Hillerød Hospital, Denmark, handling chemotherapy on a daily basis.