Publications by authors named "Haralabos Demetriades"
Effect of growth hormone on colonic anastomosis after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin: An experimental study.
World J Gastrointest Surg
August 2024
Article Synopsis
- - Growth hormone (GH) potentially enhances the healing of colonic anastomosis in rats after chemotherapy with 5-fluorouracil, bleomycin, and cisplatin, which generally impairs recovery.
- - In a study involving 80 Wistar rats, those receiving both chemotherapy and GH showed improved collagen deposition, indicated by higher hydroxyproline levels compared to those who only received chemotherapy.
- - Rats treated with GH and chemotherapy had similar body weights and bursting pressures compared to the control group, although they experienced more adhesions than untreated rats, suggesting GH might help mitigate some adverse effects of chemotherapy on wound healing.
Aim: Growth hormone is known to affect healing on the postoperative patient. The aim of the present experimental study was to evaluate the effect of systematic infusion of growth hormone on the healing of colonic anastomoses in rats.
Methods: Fourty Albino-Wistar male rats were randomly divided into two groups, a control group (CONTROL) and a growth hormone (GH) group.
Retained gallbladder remnant after laparoscopic cholecystectomy.
J Laparoendosc Adv Surg Tech A
April 2008
Background: Upper abdominal pain and other symptoms may recur after cholecystectomy, often presenting a diagnostic challenge. We will analyze 3 cases of gallbladder remnants, containing stones that presented with recurrent biliary symptoms.
Patients And Methods: Three patients have presented to our clinic with recurrent biliary symptoms, after laparoscopic cholecystectomy, over the last 5 years.