Novel colorimetric anion sensors based on N-acetylglyoxylic amides containing nitrophenyl signalling units.

N-acetylglyoxylic amides 4 and 5 bearing pendant 4-nitrophenyl and 2,4-dinitrophenyl groups respectively were synthesized and evaluated as anion sensors. A crystal structure of 4 was obtained by X-ray crystallography. Compounds 4 and 5 behaved as colorimetric sensors for CN(-) and F(-), and exhibited naked eye-detectable color changes upon the addition of these anions.

Addition of cobalamin to iron and folic acid improves hemoglobin rise in nutritional anemia.

Objective: To assess whether addition of cobalamin (cbl) to iron-folic acid will result in improved response in nutritional anemia.

Methods: This study included 150 children aged between 0.5-5 y having nutritional anemia.