Wheelchair users function and satisfaction with modified wheelchair and intermediate wheelchair services in Pakistan.

Wheelchair users with poor trunk control and postural abnormalities require additional posture support devices and wheelchair modifications to sit upright. Therefore, this study was conducted to observe the function of wheelchair users in the modified wheelchair and their satisfaction with both the modified wheelchair and intermediate wheelchair service. A descriptive study was conducted, and 14 participants were recruited through consecutive sampling.

Predicting Microvascular Invasion in Liver Transplant Recipients for Hepatocellular Carcinoma.

Background: Among primary liver tumors, hepatocellular carcinoma (HCC) is considered the most common hepatic tumor. Liver transplantation is one of the curative treatment options for HCC. However, the risk of HCC recurrence after liver transplantation varies and is influenced by various factors.

Neurological and psychiatric characterization of rapid-onset dystonia-parkinsonism over time.

Introduction: The onset of symptoms in Rapid-onset dystonia-parkinsonism (RDP) is typically over days to weeks and is often triggered by stressors like fever or childbirth. Limited information is available on how the motor and nonmotor symptoms evolve over the course of the disease. Our longitudinal study analyzed data from a cohort of RDP patients, documenting their symptoms across multiple visits.

Laccase Production Optimization from Recombinant BL21 Codon Plus Containing Novel Laccase Gene from for Removal of Wastewater Textile Dye.

The aim of the present research was the efficient degradation of industrial textile wastewater dyes using a very active cloned laccase enzyme. For this purpose, potent laccase-producing bacteria were isolated from soil samples collected from wastewater-replenished textile sites in Punjab, Pakistan. The laccase gene from locally isolated strain LI-81, identified as , was cloned into vector pET21a, which was further transformed into BL21 codon plus.

Reciprocal links between methionine metabolism, DNA repair and therapy resistance in glioblastoma.

Glioblastoma (GBM) is uniformly lethal due to profound treatment resistance. Altered cellular metabolism is a key mediator of GBM treatment resistance. Uptake of the essential sulfur-containing amino acid methionine is drastically elevated in GBMs compared to normal cells, however, it is not known how this methionine is utilized or whether it relates to GBM treatment resistance.

Patient-level analysis of the cost and variation in melatonin prescribing patterns in those under 18 in the North East of England.

Background: Melatonin is widely used to promote sleep in both normally developing children and adolescents and those with neurodevelopmental disorders. It has an evidence base as both hypnotic and chronobiotic although the optimum dose and timing remain unclear. There are now a wide variety of different preparations of melatonin both immediate and prolonged release.

Cefixime-Infused Green ZnO Nanoplatelets With Enhanced Biological Potential.

The escalating resistance to traditional antibiotics causes a significant hazard to public health, demanding innovative antimicrobial strategies. This study introduces cefixime-infused green-synthesized zinc oxide nanoplatelets (ZnO NPts) highlighting their enhanced biological potential. The successful formation of ZnO NPts and their subsequent infusion with cefixime were confirmed using various characterization techniques: UV-visible spectroscopy, Fourier transform infrared spectroscopy, x-ray diffraction, scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy, and dynamic light scattering.

FACTORS CONTRIBUTING TO ABSENTEEISM AMONG STUDENTS OF GOMAL MEDICAL COLLEGE.

Background: Absenteeism in educational settings is a significant barrier to academic success and skill development. This study investigates the socio-demographic factors contributing to absenteeism among students at Gomal Medical College MTI, Dera Ismail Khan, KPK, highlighting the importance of class attendance for fostering essential job-related skills and overall student development.

Methods: Utilizing a cross-sectional study design, this research was conducted from April to September 2023 within the Community Medicine Department of Gomal Medical College.

Interactions Between Nanoparticles and Tomato Plants: Influencing Host Physiology and the Tomato Leafminer's Molecular Response.

Tomatoes are a crucial global crop, impacting economies and livelihoods worldwide. However, pests like the tomato leafminer () significantly reduce their yield potential. Nanoparticles come as a solution to this context, promising innovative strategies for the protection of plants from pest infestation and management.

The Impact of Intra-abdominal Pressure on Perioperative Outcomes in Laparoscopic Cholecystectomy.

Introduction: Intra-abdominal pressure (IAP) is a critical factor in laparoscopic cholecystectomy, potentially affecting various perioperative outcomes. Understanding the impact of different IAP levels can guide clinical practice to optimize patient safety and recovery.

Objective: This study aimed to evaluate the effects of low, moderate, and high IAPs on perioperative outcomes in patients undergoing laparoscopic cholecystectomy.

Video-based peer assessment of collaborative teamwork in a large-scale interprofessional learning activity.

Background: The assessment of team performance within large-scale Interprofessional Learning (IPL) initiatives is an important but underexplored area. It is essential for demonstrating the effectiveness of collaborative learning outcomes in preparing students for professional practice. Using Kane's validity framework, we investigated whether peer assessment of student-produced videos depicting collaborative teamwork in an IPL activity was sufficiently valid for decision-making about team performance, and where the sources of error might lie to optimise future iterations of the assessment.

Morphology of the First Tarsometatarsal Joint and the Incidence of Arthritis and Post-operative Complications.

Introduction The first tarsometatarsal joint (TMTJ) is often overlooked regarding foot pathology or a secondary measure in most studies, despite its heavy involvement in surgical procedures and foot stability. The primary aim of this study is to assess the effect of the first TMTJ morphology on the incidence of arthritis and post-operative complications following a Lapidus procedure. Materials and methods A total of 39 feet/subjects (19 left and 20 right) were assessed by two independent reviewers.

The activity of hydrolytic enzymes and antibiotics against biofilms of bacteria isolated from industrial-scale cooling towers.

Background: Cooling towers (CTs) are crucial to myriad industrial processes, supporting thermal exchange between fluids in heat exchangers using water from lakes and rivers as coolant. However, CT water can sometimes introduce microbial contaminants that adhere to and colonize various surfaces within the CT system. These microorganisms can form biofilms, significantly hindering the system's thermal exchange efficiency.

Association Between Sleeping Quality and Risk of Breast Cancer Among Women: A Case-Control Study From Pakistan.

Background: This case-control study investigated the relationship between sleep duration and quality with the occurrence of breast cancer among women, both pre- and post-menopausal, in the northwest Khyber Pakhtunkhwa (KP) region of Pakistan.

Method: This case-control research was carried in multiple tertiary care facilities. Newly diagnosed primary breast cancer patients were recruited as cases (n = 408), and 5+ years age-matched controls (n = 408) were randomly selected from the general population.

Bibliometric Analysis of 100 Most Cited Articles in Middle East and North Africa (MENA) Region on Implant Prosthodontics.

Aim: This study aims to conduct a comprehensive analysis and scientometric evaluation of the top 100 most cited publications in the field of implant prosthodontics, authored by individuals affiliated with nations of the Middle East and North Africa (MENA) region.

Materials And Methods: In October 2023, the 100 most cited articles were gathered from the Web of Science database using the bibliometric research technique. The analysis was conducted on bibliometric indicators, including the distribution of articles over time, authorship, design of study, field of study, nature of research, contribution from various countries in MENA, international research collaboration, and most frequently used keywords by authors.

Velocity-Based-Training Frequency Impacts Changes in Muscle Morphology, Neuromuscular Performance, and Functional Capability in Persons With Parkinson's Disease.

Calaway, C, Walls, K, Levitt, H, Caplan, J, Mann, B, Martinez, K, Gastaldo, R, Haq, I, and Signorile, JF. Velocity-based-training frequency impacts changes in muscle morphology, neuromuscular performance, and functional capability in persons with Parkinson's disease. J Strength Cond Res 39(1): 99-106, 2025-Velocity-based training (VBT) positively impacts muscle morphology and performance in persons with Parkinson's disease (PD); however, optimal training frequencies for VBT in patients with PD remain undetermined.

Effect of a structured health promotional program using the self-support groups on lifestyle behavior: The .

Background: is a one-of-a-kind health promotion intervention that focuses on chronic disease prevention behaviors through peer support and social support network development. The goal of the study was to see how effective was in a city setting in India.

Materials And Methods: From July 2018 to July 2019, we used a mixed-methods intervention research design including many sites.

Eco-smart biocontrol strategies utilizing potent microbes for sustainable management of phytopathogenic diseases.

Plants have an impact on the economy because they are used in the food and medical industries. Plants are a source of macro- and micronutrients for the health of humans and animals; however, the rise in microbial diseases has put plant health and yield at risk. Because there are insufficient controls, microbial infections annually impact approximately 25 % of the world's plant crops.

Transitioning from gridlock to sustainability: advancing transport strategies for eco-friendly solutions in high-income countries.

The study aims to comprehend sustainable behaviors in high-income nations, where human-environment interactions are crucial. Increased transportation needs in industrialized countries highlight the importance of environmental challenges affecting human well-being. Railway passenger carrier, automobile energy efficiency, technology breakthroughs, financial incentives, and public-private partnerships (PPPs) affect congestion and sustainability, which the study analyses for sound policy inferences in a panel of 28 high-income nations from 2000 to 2022.